Effect of amino-acid intake on physical conditions and skin state: a randomized, double-blind, placebo-controlled, crossover trial

Journal of Clinical Biochemistry and Nutrition
Motoko TakaokaMasaru Ohtani

Abstract

The objective of this study is to elucidate the effect of a supplement enriched with l-leucine, l-arginine, and l-glutamine on body compositions/skin conditions. Healthy young women (n = 29) were allocated to a group (n = 14) receiving an amino-acid supplement (600 mg l-leucine, 250 mg l-arginine, and 300 mg l-glutamine) and a placebo group (n = 15) receiving a supplement not-containing the amino acids. The amino-acid supplement and placebo were given twice/day for 6 weeks. After a wash-out (2 months) from the 1st test, the amino-acid group received the placebo and the placebo group the amino-acid supplement. The body compositions/skin conditions were measured 4 times (day 1 and weeks 2, 4, and 6) in each test. Percentage-change of muscle mass in the amino-acid group increased up to 4 weeks (p = 0.05) and was higher than that in the placebo group (p = 0.09). Skin texture estimated by the image processing of neck skin replica tended to increase in the amino-acid group at 6 weeks compared with that at 0 week, though there was no significant intergroup difference. In conclusion, the young adult women having no fitness habit showed the significant increase of the muscle amount and improvement tendency of the skin texture by the con...Continue Reading

References

Oct 1, 1985·Quarterly Journal of Experimental Physiology : an International Journal of the Physiological Society·E A NewsholmeM S Ardawi
Jun 1, 1974·Journal of Applied Physiology·J BergströmE Vinnars
Jun 27, 1997·Biochimica Et Biophysica Acta·X Zhou, J R Thompson
Jun 4, 1999·The Journal of Nutrition·J C AnthonyD K Layman
Apr 27, 2002·The American Journal of Clinical Nutrition·Christopher DugganW Allan Walker
Aug 10, 2002·American Journal of Physiology. Endocrinology and Metabolism·Christopher J LynchThomas C Vary
Oct 30, 2003·American Journal of Physiology. Endocrinology and Metabolism·Douglas Paddon-JonesRobert R Wolfe
Feb 28, 2004·The Journal of Nutrition·Guoyao WuNancy D Turner
Apr 21, 2004·Journal of Pediatric Gastroenterology and Nutrition·S Songül YalçinLevent Oner
Nov 13, 2004·The Journal of Nutritional Biochemistry·K D TiptonR R Wolfe
Mar 30, 2005·Journal of Cellular Physiology·R CuriP Newsholme
Jan 21, 2006·The Journal of Nutrition·Masaru OhtaniKimiaki Maruyama
Mar 2, 2006·American Journal of Physiology. Endocrinology and Metabolism·Christos S KatsanosRobert R Wolfe
May 13, 2008·The American Journal of Clinical Nutrition·Gerdien C Ligthart-MelisPaul A M van Leeuwen
May 29, 2008·International Journal of Cosmetic Science·N BoyeraB A Bernard
Sep 23, 2008·The Journal of Nutrition·Jan Wernerman
Mar 27, 2009·The American Journal of Clinical Nutrition·Suzanne VerhoevenLuc J C van Loon
Oct 13, 2010·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Mohamed Z GadHossam A Elgabarty
Dec 17, 2011·Journal of Nutrition and Metabolism·Elise Mok, Régis Hankard
Mar 27, 2012·Journal of Clinical Biochemistry and Nutrition·Masaru OhtaniYasuyuki Okamoto
Apr 19, 2012·Journal of the International Society of Sports Nutrition·Benjamin WaxStanley P Brown
Aug 10, 2012·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Rena Zelig, Diane Rigassio Radler
Jan 22, 2013·The Journal of Nutritional Biochemistry·Lindsay K EllerRaylene A Reimer
Dec 23, 2014·Journal of the International Society of Sports Nutrition·Vinicius Fernandes CruzatPhilip Newsholme
May 3, 2015·Nutrition·Alessandra Zanin Zambom de SouzaPatricia Oliveira Prada
Mar 26, 2016·Journal of Clinical Biochemistry and Nutrition·Mikihiro YamanakaRyoji Nagai
Jul 29, 2017·Journal of Clinical Biochemistry and Nutrition·Kumi TominagaYuki Adachi

❮ Previous
Next ❯

Software Mentioned

Cutometer

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.