Effect of an electronic control device exposure on a methamphetamine-intoxicated animal model

Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine
D DawesJ Miner

Abstract

Because of the prevalence of methamphetamine abuse worldwide, it is not uncommon for subjects in law enforcement encounters to be methamphetamine-intoxicated. Methamphetamine has been present in arrest-related death cases in which an electronic control device (ECD) was used. The primary purpose of this study was to determine the cardiac effects of an ECD in a methamphetamine intoxication model. Sixteen anesthetized Dorset sheep (26-78 kg) received 0.0 mg/kg (control animals, n = 4), 0.5 mg/kg (n = 4), 1.0 mg/kg (n = 4), or 1.5 mg/kg (n = 4) of methamphetamine hydrochloride as a slow intravenous (IV) bolus during continuous cardiac monitoring. The animals received the following exposures in sequence from a TASER X26 ECD beginning at 30 minutes after the administration of the drug: 1) 5-second continuous exposure, 2) 15-second intermittent exposure, 3) 30-second intermittent exposure, and 4) 40-second intermittent exposure. Darts were inserted at the sternal notch and the cardiac apex, to a depth of 9 mm. Cardiac motion was determined by thoracotomy (smaller animals, < or = 32 kg) or echocardiography (larger animals, > 68 kg). Data were analyzed using descriptive statistics and chi-square tests. Animals given methamphetamine demo...Continue Reading

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Citations

Nov 26, 2009·Forensic Science, Medicine, and Pathology·James R Jauchem
Apr 2, 2013·Forensic Science, Medicine, and Pathology·Donald Murray DawesJames R Miner
Aug 27, 2014·The Journal of Emergency Medicine·Scott M KoerberGreg Flaker
Jun 8, 2012·The Journal of Emergency Medicine·William P BozemanJames E Winslow
Nov 21, 2017·Journal of Forensic Sciences·John A GibbonsMark E Peele
Feb 25, 2015·The American Journal of Forensic Medicine and Pathology·Stepan HavranekAles Linhart
Aug 23, 2019·Arteriosclerosis, Thrombosis, and Vascular Biology·Christopher G KevilA Wayne Orr

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