PMID: 20650022Jul 24, 2010Paper

Effect of an emergency department sepsis protocol on time to antibiotics in severe sepsis

CJEM
Marc FrancisDaniel Peterson

Abstract

We sought to evaluate the time to antibiotics for emergency department (ED) patients meeting criteria for severe sepsis before and after the implementation of an ED sepsis protocol. Compliance with published guidelines for time to antibiotics and initial empiric therapy in sepsis was also assessed. A retrospective chart review was conducted. Emergency department patient encounters with International Classification of Diseases codes related to severe infections were screened during a 3-month period before and after the implementation of a sepsis protocol. Encounters meeting criteria for severe sepsis were further assessed. The time to initiation of antibiotics was determined as well as the initial choice of antimicrobial therapy based on the presumed source of infection. We reviewed 213 unique ED patient encounters meeting criteria for severe sepsis. Analysis of the period before implementation showed a median time from the time criteria for severe sepsis were met to delivery of antibiotics of 163 minutes (95% confidence interval [CI] 124 to 210 min). Analysis of the period after implementation of the protocol revealed a median time of 79 minutes (95% CI 64 to 94 min), representing an overall reduction of 84 minutes (95% CI 42 t...Continue Reading

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Citations

Sep 17, 2014·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Amy LoPatrick Chan
Jan 26, 2017·The British Journal of Surgery·UNKNOWN UK National Surgical Research Collaborative
Jun 22, 2020·European Journal of Clinical Investigation·Matthaios Papadimitriou-OlivgerisHervé Duplain
Aug 27, 2015·Critical Care : the Official Journal of the Critical Care Forum·José Garnacho-MonteroJosé María López-Sánchez
Aug 7, 2012·Current Infectious Disease Reports·Carley RileyDerek S Wheeler
Jan 1, 2014·Journal for Healthcare Quality : Official Publication of the National Association for Healthcare Quality·Catherine PatockaEli Segal
Jul 25, 2021·The International Journal of Pharmacy Practice·Helen Y WangBarbara Gatton
May 22, 2018·Journal of Emergency Nursing : JEN : Official Publication of the Emergency Department Nurses Association·Elizabeth N ReichJames A Rankin

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