PMID: 6168586Aug 1, 1981Paper

Effect of an infusion with middle molecular weight hydroxyethyl starch (HAES-steril 10%) on the flow properties of blood in healthy probands

Infusionstherapie Und Klinische Ernährung
H LandgrafC Vogel

Abstract

Ten healthy volunteers received infusions of 500 ml of a 10% solution of middle-molecular-weight hydroxy-ethyl-starch (HES 200, HAES-steril 10%) within 30 min. Measurements of hemorheological parameters before and up to 3 hrs after infusion revealed a statistically significant decrease of whole-blood viscosity and a slight, but also statistically significant increase of plasma viscosity. RBC filterability and RBC aggregation remained unchanged. The data presented show that despite of a relatively high molecular weight of the infused HES-solution which is responsible for the relatively long intravascular persistence, the flow properties of blood as a whole are positively influenced.

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