PMID: 9636905Jun 24, 1998Paper

Effect of aortic cannula characteristics and blood velocity on transcranial doppler-detected microemboli during cardiopulmonary bypass

Journal of Cardiothoracic and Vascular Anesthesia
M BenaroiaL Errett

Abstract

Cerebral microemboli are responsible to a large extent for the neuropsychiatric deficits after cardiac surgery. Differences in cannula size during cardiopulmonary bypass (CPB) will result in different velocities of blood exiting the aortic cannula. This study determined whether the number of transcranial Doppler (TCD)-detected emboli in the middle cerebral artery (MCA) during CPB correlated with blood speed or the direction of flow as determined by the shape of the aortic cannula. Patients were studied prospectively for evidence of TCD-detected emboli. If patients met the inclusion criteria, the choice of cannula was determined by surgical preference. All studies were conducted at a single tertiary care academic cardiac surgery hospital by a single observer. Thirty-two patients undergoing first-time elective aortocoronary bypass surgery who were free of neurologic dysfunction or peripheral vascular disease and weighed 60 to 85 kg were studied. Patients who had other concurrent cardiac operations or who were in cardiogenic shock were excluded. Three aortic cannula types for elective aortocoronary bypass surgery were used: 24F curved (n = 19), 24F straight (n = 6), and 22F straight (n = 7), with internal diameters (IDs) of 7.2, 6...Continue Reading

References

Feb 1, 1991·The Annals of Thoracic Surgery·J van der Linden, H Casimir-Ahn
Mar 1, 1990·Stroke; a Journal of Cerebral Circulation·M P SpencerL R Sauvage
May 1, 1995·The Annals of Thoracic Surgery·A J BakerC D Mazer
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Mar 1, 1995·The Annals of Thoracic Surgery·E A GrossiS B Colvin
Jul 1, 1994·Stroke; a Journal of Cerebral Circulation·W PugsleyS Newman

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