PMID: 6162702Apr 1, 1980Paper

Effect of aprotinin on growth of 3-methylcholanthrene-induced squamous cell-carcinoma in mice

Gann = Gan
M Ohkoshi

Abstract

The effect of aprotinin (Trasylol), a broad-spectrum inhibitor of proteinase, was studied on the growth of murine squamous cell carcinoma induced by 3-methylcholanthrene. In this tumor system, the administration of aprotinin was therapeutically effective. Histologically, aprotinin-treated tumor showed a significant hyperkeratosis.

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