Abstract
The phytochemical constituents of aqueous extract of Bulbine natalensis (Baker) stem and its effect on male rat sexual behaviour were evaluated for 7 days. Phytochemical screening revealed the presence of saponins, cardiac glycoside, tannins, alkaloids and anthraquinones. Administration of the extract at the doses of 25 and 50 mg/kg body weight resulted in the significant increase (p < 0.05) in mount frequency, intromission frequency, ejaculatory latency, ejaculation frequency, serum testosterone and luteinizing hormone concentrations, computed indices of sexual behaviour, erection, quick flips, long flips and total penile reflexes whereas the mount latency, intromission latency and post-ejaculatory interval were significantly decreased (p < 0.05) throughout the experimental period. The 100 mg/kg body weight of the extract produced contrasting pattern to the lower doses of the extract in all the parameters of sexual behaviour monitored throughout the experimental period. The results are indicative of prosexual stimulatory potentials of Bulbine natalensis in male rats. The aqueous extract of Bulbine natalensis stem at these doses (25 and 50 mg/kg body weight) may be used in the management of disorders of desire/libido, premature...Continue Reading
References
Aug 1, 1988·Endocrine Reviews·W L Miller
Nov 1, 1970·Physiology & Behavior·D A Dewsbury, H N Davis
Mar 26, 1981·European Journal of Pharmacology·H SzechtmanR Simantov
Jun 1, 1995·Endocrinology·A P HikimR S Swerdloff
Dec 1, 1993·Endocrinology·C WangA P Sinha-Hikim
May 1, 1997·Brain Research. Brain Research Protocols·A Agmo
Jul 2, 1998·The Journal of Urology·E Ernst, M H Pittler
Oct 7, 1998·Physiology & Behavior·L L MurphyJ S Ferraro
Jun 4, 1999·Trends in Pharmacological Sciences·A L Harvey
Jun 13, 2000·International Journal of Andrology·A Adimoelja
Apr 12, 2001·Journal of Ethnopharmacology·A F CiceroR Arletti
Jul 20, 2002·Life Sciences·K GauthamanR N V Prasad
Feb 20, 2003·Phytochemistry·Siegfried E DrewesFatima Khan
Jun 14, 2003·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Kalamegam GauthamanR N V Prasad
Aug 15, 2003·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Andre T GuayUNKNOWN American Association of Clinical Endocrinologists Male Sexual Dysfunction Task Force
Nov 9, 2004·BMC Complementary and Alternative Medicine· TajuddinIqbal Ahmad Qasmi
Nov 11, 2005·Asian Journal of Andrology·M T YakubuA T Oladiji
Dec 11, 2007·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Kalamegam Gauthaman, Adaikan P Ganesan
Citations
Feb 3, 2012·BMC Complementary and Alternative Medicine·Cao JianFengChen KaoShan
Apr 4, 2013·BMC Complementary and Alternative Medicine·Modeste Wankeu-NyaAlbert Kamanyi
Jan 1, 2012·African Journal of Traditional, Complementary, and Alternative Medicines : AJTCAM·M T YakubuA J Afolayan
Jan 1, 2012·African Journal of Traditional, Complementary, and Alternative Medicines : AJTCAM·M T Yakubu, A L Quadri
Jul 3, 2009·The Journal of Sexual Medicine·Gokhan TemeltasMurat Lekili
May 5, 2009·Theriogenology·M T Yakubu, A J Afolayan
Sep 29, 2011·Andrologia·M T YakubuM A Akanji
Mar 8, 2013·Andrologia·M C SolomonR R Henkel
Oct 4, 2015·BMC Complementary and Alternative Medicine·Gerda FoucheJeremiah Senabe
Jul 10, 2012·Journal of Ethnopharmacology·H S Abdillahi, J Van Staden
Jun 7, 2013·Pharmaceutical Biology·Antoine Kada SandaPierre Kamtchouing
Sep 13, 2014·BioMed Research International·Nagendra Singh ChauhanMayank Thakur
Aug 26, 2014·Asian Pacific Journal of Tropical Medicine·M Wankeu-NyaA Kamanyi
Nov 27, 2015·Asian Journal of Andrology·Zhi-Jun ZangChun-Hua Deng
Jul 12, 2017·BMC Complementary and Alternative Medicine·Joseph O Erhabor, MacDonald Idu
Dec 2, 2017·BMC Complementary and Alternative Medicine·Xingli TangXilin Hou
Sep 9, 2009·Journal of Medicinal Food·A J Afolayan, M T Yakubu
Oct 19, 2019·Andrology·A F Ajayi, R E Akhigbe
Apr 2, 2020·Journal of Basic and Clinical Physiology and Pharmacology·Arnab BanerjeeBithin Kumar Maji
Aug 25, 2010·Pharmaceutical Biology·Anofi Omotayo Tom AshafaAnthony Jide Afolayan
May 22, 2019·BioMed Research International·Muhammad MajidIhsan-Ul Haq
Dec 31, 2020·Andrologia·David Tolulope OluwoleAyodeji Folorunsho Ajayi
Dec 16, 2020·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Islam HusainShabana I Khan
Jun 4, 2020·Journal of Ethnopharmacology·Olusola Bodede, Gerhard Prinsloo
Apr 24, 2021·Andrologia·Mariette SindeteAnne-Cécile Ribou
May 28, 2021·Journal of AOAC International·Bharathi AvulaIkhlas A Khan
Jul 30, 2021·Scientific Reports·Maged S Abdel-KaderObaid Afzal
Aug 17, 2020·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Nelisiwe Prenate MasukuSogolo Lucky Lebelo
Aug 7, 2021·Planta medica·Islam HusainShabana I Khan
Jul 10, 2019·Journal of Natural Products·Ji-Yeong BaeIkhlas A Khan
Dec 18, 2021·Diabetic Medicine : a Journal of the British Diabetic Association·Sunday O OyedemiShanta J Persaud