Effect of artificial liver support system on patients with severe viral hepatitis: a study of four hundred cases

World Journal of Gastroenterology : WJG
Lan-Juan LiSu-Zhen Fu

Abstract

To assess the effect of artificial liver support system (ALSS) on patients with severe viral hepatitis, who were divided into treatment group and control group. Four hundred in-hospital patients enrolled during 1995-2003 who received ALSS therapy were studied as the treatment group. Four hundred in-hospital patients enrolled during 1986-1994 who received other medical therapies served as the control group. The methods of ALSS used included plasma exchange, hemoperfusion, hemofiltration, continuous hemodiafiltration (CHDF). The effect of ALSS treatment was studied in patients at different stages of the disease. The cure rate of acute and subacute severe hepatitis in the treatment group was 78.9% (30/38), and was 11.9% (5/42) in the control group. The improved rate of chronic severe hepatitis in the treatment group was 43.4% (157/362), and was 15.4% (55/358) in the control group. We found that patients treated with ALSS in the early or middle stage of the disease had much higher survival rates than patients in the end stage of the disease. ALSS is an effective and safe therapy for severe viral hepatitis.

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Citations

Apr 18, 2014·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Hirokazu SatoRyota Hokari
Nov 23, 2011·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Hua LiuYu-Ying Feng
Jul 23, 2013·Liver International : Official Journal of the International Association for the Study of the Liver·Xiaojun DongHai Li
Apr 27, 2011·Seminars in Dialysis·Jorge CerdáKhajohn Tiranathanagul
May 21, 2016·International Journal of Clinical Practice·M-L ZhangS-S Zheng
Apr 5, 2008·Current Opinion in Critical Care·Jason Phua, Kang Hoe Lee
May 11, 2006·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Lan Juan LiYue Mei Chen
Nov 16, 2013·Artificial Cells, Nanomedicine, and Biotechnology·Vladimir G Nikolaev, Vitaliy A Samsonov
Jul 11, 2014·The International Journal of Artificial Organs·Qi XiaLanjuan Li
Sep 4, 2015·World Journal of Gastroenterology : WJG·Pi-Qi ZhouZhi-Hong Weng
Nov 10, 2007·The International Journal of Artificial Organs·Y-S ChenL-J Li

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