Aug 21, 1976

Effect of atenolol on ventilatory and cardiac function in asthma

British Medical Journal
J S Vilsvik, J Schaanning


The effects on ventilatory and cardiac function of atenolol, a new cardioselective beta-adrenoceptor blocking agent, were compared with those of practolol in a double-blind trial in 12 patients with asthma. Both drugs impaired ventilatory function--atenolol insignificantly and practolol significantly. Atenolol was if anything more cardioselective than practolol. Neither drug interfered significantly with the bronchodilator response to inhaled isoprenaline. Atenolol is suitable for use in patients for whom practolol would formerly have been chosen because of its cardioselectivity.

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Mentioned in this Paper

Peak Expiratory Flow Rate Measurement
Diastolic Blood Pressure
Bronchodilator Agents
Forced Expiratory Volume Function
Clinical Trials

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