Effect of Atlas Vertebrae Realignment in Subjects with Migraine: An Observational Pilot Study

BioMed Research International
H Charles WoodfieldJames N Scott

Abstract

Introduction. In a migraine case study, headache symptoms significantly decreased with an accompanying increase in intracranial compliance index following atlas vertebrae realignment. This observational pilot study followed eleven neurologist diagnosed migraine subjects to determine if the case findings were repeatable at baseline, week four, and week eight, following a National Upper Cervical Chiropractic Association intervention. Secondary outcomes consisted of migraine-specific quality of life measures. Methods. After examination by a neurologist, volunteers signed consent forms and completed baseline migraine-specific outcomes. Presence of atlas misalignment allowed study inclusion, permitting baseline MRI data collection. Chiropractic care continued for eight weeks. Postintervention reimaging occurred at week four and week eight concomitant with migraine-specific outcomes measurement. Results. Five of eleven subjects exhibited an increase in the primary outcome, intracranial compliance; however, mean overall change showed no statistical significance. End of study mean changes in migraine-specific outcome assessments, the secondary outcome, revealed clinically significant improvement in symptoms with a decrease in headache ...Continue Reading

References

Jan 1, 1978·The American Journal of Physiology·M KumadaD J Reis
Dec 1, 1995·Radiology·V N Cassar-PullicinoW el Masry
Mar 4, 1998·Annals of Neurology·P J Goadsby, H L Fields
Feb 23, 1999·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·A May, P J Goadsby
Feb 14, 2002·Carbohydrate Research·Wen BianKozo Ogawa
Jul 26, 2002·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·W J Becker
Dec 4, 2003·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·M KosinskiS Tepper
Oct 1, 1950·Physiological Reviews·H W MAGOUN
May 18, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·M Czosnyka, J D Pickard
May 28, 2004·Journal of Environmental Radioactivity·A LikarG Omahen
May 25, 2005·Cephalalgia : an International Journal of Headache·S D SilbersteinUNKNOWN International Headache Society
Jul 5, 2007·Journal of Magnetic Resonance Imaging : JMRI·Tosiaki MiyatiRoger Luechinger
Jun 14, 2008·Headache·Peter J Goadsby, Richard Hargreaves
Jun 24, 2008·British Journal of Neurosurgery·I MarshallI Whittle
Apr 9, 2009·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Souraya Stoquart-ElsankariOlivier Balédent
Oct 16, 2009·Cephalalgia : an International Journal of Headache·J C ColeM F T Rupnow
Mar 6, 2010·AJNR. American Journal of Neuroradiology·Andrew L WentlandV M Haughton
May 18, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Karin Meissner
May 31, 2011·Journal of Manipulative and Physiological Therapeutics·H Charles WoodfieldDale F Johnson
Jun 22, 2012·Critical Care Research and Practice·P H RaboelB Romner
Feb 2, 2013·Journal of Magnetic Resonance Imaging : JMRI·Inga KoerteBirgit Ertl-Wagner
Jul 12, 2013·Cephalalgia : an International Journal of Headache·Antonia F H SmeltJeanet W Blom

❮ Previous
Next ❯

Methods Mentioned

BETA
pharmacotherapy

Clinical Trials Mentioned

NCT01980927

Software Mentioned

NUCCA
MSQL
CHAMP
MRICP

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.