Effect of Atypical Antipsychotic on Blood Pressure in Inpatients with Schizophrenia of Prof. Dr. Soerojo Mental Health Hospital Magelang

Journal of Pharmacy & Bioallied Sciences
Haafizah DaniaRizky Abdulah

Abstract

Schizophrenia ranks the top of all mental disorders with poor prognosis. Central Java Province is in the top five of schizophrenia incidents in Indonesia. Antipsychotic is the main therapy for schizophrenia, which is divided into 2, atypical and typical. The atypical antipsychotic is more preferable because of the minimal effect of the extrapyramidal syndrome but affects the blood pressure. To analyze the blood pressure of schizophrenia inpatients during the pre and post-use of atypical antipsychotics in RSJ Prof. Dr. Soerojo Magelang. This study was an observational study with cohort retrospective methods. The research was approved and reviewed by the committee of ethics and law of Prof. Dr. Soerojo Mental Hospital. The inclusion criteria are those diagnosed with schizophrenia based on Diagnostic and Statistical Manual of Mental Disorders-IV (DSM IV), aged about 17-55 years old, receiving antipsychotic atypical therapy for at least 3 months.The exclusion criteria are inpatients who also receive antidepressants and antihypertension, have a history of cardiovascular disease and hypertension, and incomplete medical records. Wilcoxon, Mann-Whitney, and Kruskal-Wallis test. The result of this study most of them were treated using c...Continue Reading

References

Nov 11, 2005·Journal of Psychopharmacology·Peter Haddad
Feb 23, 2008·Schizophrenia Research·Rajiv TandonHenry A Nasrallah
Feb 9, 2011·Archives of General Psychiatry·Debra L Foley, Katherine I Morley
Sep 12, 2013·Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology·You-Kyung KoJong-Il Lee
Oct 18, 2014·The British Journal of Psychiatry : the Journal of Mental Science·Mike J CrawfordDavid Shiers

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Software Mentioned

Statistical Package for the Social Sciences ( SPSS )

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