Effect of Bariatric Surgery on the Cardiovascular System in Obese Cases with Pulmonary Hypertension.

Obesity Surgery
Ahmed Abdallah SalmanHani Maurice Sabri Mikhail

Abstract

Recently, the incidence of obesity has been rising exponentially. Clinical studies have demonstrated that different subtypes of pulmonary hypertension (PH) are linked to obesity. The current work mainly aims to assess the impact of laparoscopic sleeve gastrectomy (LSG) on PH in a cohort of obese cases. The present prospective work included 37 obese cases with PH for whom LSG was done. Only cases with PH and presurgical right ventricular systolic pressure (RVSP) ≥ 35 mmHg using Doppler echocardiogram were enrolled. Fifteen months later, patients were reassessed regarding new weight and BMI in addition to changes in RVSP. At the end of follow-up, the average BMI improved from 45.8 + 3.9 to 33.8 + 2.5 Kg/m2 (p value < 0.001). Improved right ventricular (RV) size compared to baseline echo was observed in 20 patients. RV size decreased from 2.68 + 0.44 cm to 2.34 + 0.36 cm (p value < 0.001). Notable decrease of PH to less than 30 mmHg occurred in 33 patients. Mean RVSP decreased from 39.62 + 2.1 to 31.81 + 3.1 mmHg (p value < 0.001). LSG significantly decreased the requirements for PH drugs and supplemental oxygen therapy. The current work suggests that LSG-induced weight loss may result in a considerable decrease in pulmonary press...Continue Reading

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Citations

May 22, 2021·The Journal of Clinical Endocrinology and Metabolism·Assaf BuchNaftali Stern
Aug 19, 2021·The Journal of Clinical Endocrinology and Metabolism·Assaf BuchNaftali Stern
Jun 16, 2021·Current Opinion in Pulmonary Medicine·Allyson L Hughes, Anna R Hemnes

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