Effect of bioactive glass nanoparticles on biological properties of PLGA/collagen scaffold

Progress in Biomaterials
Samira NokhastehHojjat Naderi-Meshkin

Abstract

Bioactive glasses have shown some interesting biological properties such as biocompatibility, biodegradation, and angiogenesis in skin tissue engineering. In the current research, the effects of MgO- or CoO-doped 64S bioactive glass with a composition of 64 SiO2-26 CaO-5 P2O5-5 MgO or CoO (mol%) were studied in relation with biological properties of electrospun [poly(lactic-co-glycolic acid) (PLGA)/collagen]. PLGA/collagen samples were rinsed in suspension of bioactive glass nanoparticles in distilled water with a concentration of 0.1 w/v and then freeze dried. Cell adhesion, viability, angiogenesis, and ionic release were performed and tested in culture medium containing fibroblast cells. Attachment and viability of fibroblast cells were increased significantly in bioglass-coated samples, while shrinkage in PLGA/collagen scaffold was reduced by the addition of bioactive glass. Vascular endothelial growth factor secretion in coated scaffold was dropped compared to the uncoated samples. This could be attributed to the fast degradation of glass nanoparticles, according to the inductively coupled plasma-atomic emission spectroscopy results.

References

Apr 12, 2002·Journal of Biomedical Materials Research·Wan-Ju LiFrank K Ko
May 15, 2002·Journal of Biomedical Materials Research·P SepulvedaL L Hench
May 23, 2002·Antimicrobial Agents and Chemotherapy·Maria BellantoneLarry L Hench
Nov 19, 2003·Journal of Biomedical Materials Research. Part a·J J BlakerA R Boccaccini
Oct 8, 2004·Journal of Biomedical Materials Research. Part a·Ana I TeixeiraChristopher J Murphy
Aug 6, 2005·Journal of Biomedical Materials Research. Part a·Richard M DayAlastair Forbes
Nov 24, 2006·Journal of Materials Science. Materials in Medicine·Larry L Hench
Dec 1, 2006·Acta Biomaterialia·Anbalagan BalamuruganJose M F Ferreira
Dec 1, 2007·Pharmaceutical Research·Ann Leu, J Kent Leach
Dec 7, 2007·Biomaterials·Heather M PowellSteven T Boyce
Apr 24, 2008·Journal of Biomedical Materials Research. Part a·Zhenhuan ZhengXiufang Zhang
Jul 22, 2008·Biomaterials·Sangamesh G KumbarCato T Laurencin
Oct 17, 2009·Tissue Engineering. Part B, Reviews·Alejandro A GorustovichAldo R Boccaccini
Mar 23, 2011·Acta Biomaterialia·Mohamed N RahamanAntoni P Tomsia
Nov 10, 2012·Journal of Biomedical Materials Research. Part a·Abbas Ali Imani FooladiMohammad Reza Nourani
Feb 23, 2013·Tissue Engineering. Part a·Shaojie WangHimanshu Jain
Feb 23, 2013·Journal of Materials Science. Materials in Medicine·Gabriela E VargasAlejandro A Gorustovich
Sep 10, 2013·Trends in Biotechnology·Susmita BoseAmit Bandyopadhyay
May 6, 2015·ACS Applied Materials & Interfaces·Changhai RuYu Sun
May 22, 2016·Materials Science & Engineering. C, Materials for Biological Applications·A R SadeghiA Mahdizadeh
Jul 6, 2010·Materials·Lutz-Christian Gerhardt, Aldo R Boccaccini
May 7, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Xiufang LiMingzhong Li
Aug 21, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Shiva NaseriShowan N Nazhat

❮ Previous
Next ❯

Citations

Nov 30, 2019·Nanomedicine·Michael J HillMorteza Mahmoudi
Jun 25, 2020·Journal of Biomaterials Science. Polymer Edition·Thaís Larissa do Amaral MontanheiroGilmar Patrocínio Thim
Sep 19, 2020·International Journal of Molecular Sciences·Sathish Sundar Dhilip Kumar, Heidi Abrahamse
Jan 6, 2021·Journal of Nanobiotechnology·Hamed NosratiZohreh Alizadeh
Jul 15, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Chen YuanYubao Li
Nov 2, 2021·Progress in Biomaterials·Parisa NikpourSayed Mahmood Rabiee

❮ Previous
Next ❯

Methods Mentioned

BETA
enzyme-linked immunosorbent assay

Related Concepts

Related Feeds

Arterial-Venous in Development & Disease

Arterial-venous development may play a crucial role in cardiovascular diseases. Here is the latest research.

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.

Related Papers

Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]
W F BauerW A Propp
Regenerative Biomaterials
Alireza Sadeghi-AvalshahrMeysam Mahdavi-Shahri
Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas
A R RosaP Pranke
© 2022 Meta ULC. All rights reserved