Effect of biventricular pacing on left ventricular outflow tract pressure gradient in a patient with hypertrophic cardiomyopathy and normal interventricular conduction

Journal of Cardiovascular Electrophysiology
Baki KomsuogluDilek Ural

Abstract

We report a case of hypertrophic obstructive cardiomyopathy (HOCM) that was markedly improved by biventricular pacing. A 55-year-old woman with HOCM presented with palpitation and presyncope. Electrophysiologic study revealed an atrioventricular nodal reentrant tachycardia. After radiofrequency catheter ablation, a Mobitz type II atrioventricular block developed and a permanent pacemaker implantation was decided. Cardiac catheterization showed a left ventricular outflow tract (LVOT) gradient of 130 mmHg. Right dual-chamber and atrial-synchronous left ventricular epicardial pacing failed to reduce the gradient. After biventricular pacing, LVOT gradient decreased to 20 mmHg. Biventricular pacing may be an alternative therapy for patients with HOCM.

References

Nov 9, 2004·Lancet·Richard G TrohmanSergio L Pinski

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Citations

Oct 19, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Antonio BerruezoJosep Brugada
Aug 13, 2011·Pacing and Clinical Electrophysiology : PACE·Radosław LenarczykZbigniew Kalarus
Feb 7, 2015·Clinical Medicine Insights. Cardiology·Brian A Houston, Gerin R Stevens
Feb 6, 2018·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Antonio BerruezoJosep Brugada
Dec 23, 2015·Echo Research and Practice·Antonis PantazisSilvia Castelletti
Nov 4, 2006·Expert Review of Cardiovascular Therapy·Anjan S Batra, Seshadri Balaji
Jul 3, 2013·Journal of Cardiovascular Medicine·Daniele MasaronePier D Lambiase
Jan 17, 2007·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Houman AshrafianAndrew G Mitchell
Jul 29, 2021·JACC. Case Reports·Hellmuth S vH WeichAnton Doubell

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