Effect of bombesin on extragastric gastrin in man.

The American Journal of Digestive Diseases
N BassoV Speranza

Abstract

The effect of a protein test meal and a bombesin infusion on extragastric gastrin levels was studied in patients with truncal vagotomy, antrectomy, and gastroduodenostomy or gastrojejunostomy and in patients with total gastrectomy. In patients with vagotomy, antrectomy, and gastroduodenostomy and in patients with total gastrectomy the gastrin levels were raised by 33% and 35%, respectively, from basal after test meal, while during BBS infusion gastrin values decreased by 25% and 30%, respectively, from basal. In patients with vagotomy, antrectomy, and gastrojejunostomy, test meal and BBS infusion did not significantly alter basal gastrin values. It is concluded that BBS does not stimulate extragastric gastrin.

References

Oct 1, 1972·Scandinavian Journal of Clinical and Laboratory Investigation·J F RehfeldB Rubin
Oct 1, 1974·British Journal of Pharmacology·G BertacciniN Sopranzi
Oct 1, 1974·British Journal of Pharmacology·V ErspamerN Sopranzi
Jan 11, 1973·The New England Journal of Medicine·J E McGuigan, W L Trudeau
Jun 1, 1973·Scandinavian Journal of Clinical and Laboratory Investigation·J F Rehfeld, F Stadil

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Citations

Feb 1, 1977·The American Journal of Digestive Diseases·N BassoV Speranza
May 1, 1985·Regulatory Peptides·B AnnibaleG Delle Fave
Jun 16, 1988·The New England Journal of Medicine·G den HartogC B Lamers
Jan 1, 1979·Acta Physiologica Scandinavica·B Holstein
Sep 20, 1979·World Journal of Surgery·N BassoV Speranza
Jun 11, 2003·Scandinavian Journal of Gastroenterology·W P M HopmanJ B M J Jansen
Aug 1, 1977·American Journal of Surgery·N BassoV Speranza
Jan 1, 1981·American Journal of Surgery·V SperanzaA Paduos
Feb 1, 1981·The British Journal of Surgery·N BassoV Speranza
Jan 1, 2003·Scandinavian Journal of Gastroenterology·W P M Hopman J B M J Jansen
Aug 1, 1978·The American Journal of Physiology·R J MayJ D Gardner

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