Effect of brimonidine tartrate 0.15% on night-vision difficulty and contrast testing after refractive surgery

Journal of Cataract and Refractive Surgery
Jayson D EdwardsJeff C Rabin

Abstract

To evaluate the efficacy of brimonidine tartrate ophthalmic solution 0.15% in patients with night-vision difficulties after laser refractive surgery. Center for Refractive Surgery, Walter Reed Army Medical Center, Washington, District of Columbia, USA. Six patients with significant night-vision complaints after refractive surgery were enrolled in this study after other treatable causes of night-vision difficulty such as residual refractive error and dry eye were excluded. Low-contrast visual acuity (LCVA) over a range of contrasts (1.25% to 25%) and small letter contrast sensitivity were tested at photopic (100 cd/m(2)) and mesopic (1 cd/m(2)) luminance levels, with and without a standard glare source. Testing was performed before brimonidine tartrate ophthalmic solution 0.15% was administered. Measurements were repeated 1 hour and 1 month after the use of brimonidine tartrate. One hour after using brimonidine tartrate 0.15% solution, patients had significant improvement in LCVA, LCVA with glare, and contrast sensitivity. After 1 month of treatment, all 6 patients reported subjective improvement in night vision and there was a significant difference in performance in mesopic LCVA and mesopic LCVA with glare. The mean pupil size...Continue Reading

References

Nov 1, 1996·Journal of Cataract and Refractive Surgery·F A EgginkJ M den Boon
Feb 1, 1997·The British Journal of Ophthalmology·U NiesenI Schipper
Apr 8, 1998·Journal of Cataract and Refractive Surgery·J J Pérez-SantonjaJ L Alió
Aug 26, 1998·Archives of Ophthalmology·C E MartínezH C Howland
Jan 15, 1999·Journal of Cataract and Refractive Surgery·B S Boxer WachlerR R Krueger
Mar 20, 2001·Journal of Cataract and Refractive Surgery·M MrochenT Seiler
Apr 20, 2001·Journal of Cataract and Refractive Surgery·J A HovanesianR K Maloney
Oct 22, 2002·Journal of Cataract and Refractive Surgery·Ioannis G PallikarisAristofanis I Pallikaris
Dec 31, 2002·Survey of Ophthalmology·Nancy I Fan-PaulGeorge J Florakis
Aug 15, 2003·Ophthalmology·Steven C SchallhornLinda B Bourque
Jul 6, 2004·American Journal of Ophthalmology·Sandra M BrownDavid L McCartney
Aug 18, 2004·Journal of Cataract and Refractive Surgery·John E ThordsenRichard Stutzman
Aug 18, 2004·Journal of Cataract and Refractive Surgery·Anat KeslerMoshe Lazar

❮ Previous
Next ❯

Citations

Sep 30, 2010·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Ozgur ArtunayHalil Bahcecioglu
Feb 22, 2011·Journal of Cataract and Refractive Surgery·Gabi ShemeshAnat Kesler
Sep 29, 2009·Journal of Cataract and Refractive Surgery·Sandra Brown
Sep 7, 2016·Journal of Refractive Surgery·José R JiménezLuis Jiménez Del Barco
Dec 17, 2016·Eye and Vision·Almamoun Abdelkader, Herbert E Kaufman
Sep 15, 2020·Journal of Cataract and Refractive Surgery·Gary J L FosterAbhay R Vasavada
Jul 13, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Mitra NejadJohn D Bartlett
Jun 19, 2009·Current Opinion in Ophthalmology

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.