Effect of brimonidine tartrate 0.15% on scotopic pupil size and upper eyelid position: controlled trial.

Eye
Ibrahim TuncerEsat Çınar

Abstract

To evaluate the effect of brimonidine tartrate 0.15% ophthalmic solution on pupil size under scotopic condition and upper eyelid position. This study comprised 72 eyes of 36 healthy subjects. A single drop of brimonidine tartrate 0.15% ophthalmic solution was instilled in the right eye and artificial tear was instilled in the left eye. Pupil size was measured using an infra-red pupillometer under scotopic condition before and at 30 min, 2, 4, 6, 8 and 10 h after instillation. Measurement of margin reflex distance 1 (MRD1) was performed using a millimetre ruler before and after at 10 min after instillation. The mean age of the subjects was 32.19 ± 11.43 years (range 10-52 years), 17 were female and 19 were male. Before brimonidine instillation, the mean pupil size was 6.09 ± 1.03 mm in the brimonidine eyes and 6.06 ± 1.04 mm in the control eyes. There was a significant decrease in mean pupil size at 30 min (4.45 ± 1.04), 2 h (4.49 ± 1.06), 4 h (4.59 ± 1.06), 6 h (4.89 ± 1.06) and 8 h (5.38 ± 1.02) after instillation compared to before in brimonidine eyes (p < 0.001 for all). There was a significant miosis continued for at least 6 h (5.95 ± 1.03) in control eyes (p < 0.001). There was no significant change in MRD1, before and aft...Continue Reading

References

Aug 1, 1975·Archives of Ophthalmology·A M Putterman, M J Urist
Jun 15, 1991·American Journal of Ophthalmology·P M MundenK D Carter
Jan 1, 1997·Ophthalmology·R J DerickJ F Stoecker
Aug 26, 1998·Ophthalmology·L MastropasquaM Ciancaglini
Jan 15, 1999·Journal of Cataract and Refractive Surgery·T Kohnen
Apr 6, 1999·Ophthalmic Plastic and Reconstructive Surgery·B Esmaeli-GutsteinJ T Harvey
Aug 15, 2003·Ophthalmology·Steven C SchallhornLinda B Bourque
Aug 18, 2004·Journal of Cataract and Refractive Surgery·John E ThordsenRichard Stutzman
Aug 18, 2004·Journal of Cataract and Refractive Surgery·Anat KeslerMoshe Lazar
Jul 30, 2005·Ophthalmic Plastic and Reconstructive Surgery·Heather C BaldwinRamona Khooshabeh
Dec 13, 2006·Journal of Drug Targeting·Muhammad AbdulrazikSimon Benita
Sep 21, 2007·Ophthalmic Plastic and Reconstructive Surgery·Bentley C SkibellDan D Deangelis
Sep 29, 2007·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Vanessa M GerenteAugusto Paranhos
Jul 23, 2008·Ophthalmic Plastic and Reconstructive Surgery·Bülent Yazici, Umit Beden
Feb 22, 2011·Journal of Cataract and Refractive Surgery·Gabi ShemeshAnat Kesler
Jun 10, 2015·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Kenneth D SteinsapirCynthia A Boxrud
Dec 9, 2016·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Taís B MendonçaFernando Procianoy

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