PMID: 7021992Jun 1, 1981Paper

Effect of caerulein on blood glucose, serum insulin, glucagon, prolactin and growth hormone before and after oral glucose load in healthy volunteers and diabetic patients (author's transl)

Klinische Wochenschrift
R LandgrafM M Landgraf-Leurs

Abstract

Eleven healthy volunteers, five type I diabetics, and one type II diabetic man were examined. After an overnight fast caerulein (20 ng/kg) was injected intravenously and 60 min later an oral glucose tolerance test was performed with 100 g glucose in the normals and 25 g glucose in the diabetics. Blood pressure, pulse rate, blood glucose, serum insulin, glucagon, prolactin and growth hormone values were measured during the whole period of 240 min and compared with the same parameters in control tests in the same persons without caerulein application. None of the measured parameters were significantly influenced by caerulein. It is therefore concluded that in contrast to the stimulation of the exocrine pancreas functions of the endocrine pancreas, the pituitary gland and glucose tolerance are unchanged after caerulein.

References

Apr 1, 1967·The Journal of Clinical Investigation·R H UngerA M Eisentraut
Feb 1, 1973·Japanese Journal of Pharmacology·N NakamuraH Takahira
Jan 1, 1972·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·F FalluccaD Andreani
Oct 1, 1968·British Journal of Pharmacology·G BertacciniM Impicciatore
Nov 1, 1972·Toxicology and Applied Pharmacology·T ChieliE Solcia
Oct 1, 1971·The Journal of Clinical Investigation·J Iversen
Apr 1, 1968·Archives of Biochemistry and Biophysics·A AnastasiR Endean
Oct 1, 1968·British Journal of Pharmacology·G BertacciniM Impicciatore
Aug 29, 1980·Deutsche medizinische Wochenschrift·B NeidhardtH J König
Jul 1, 1963·The Biochemical Journal·C N HALES, P J RANDLE
Dec 1, 1961·Klinische Wochenschrift·F H SCHMIDT

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