PMID: 6940475Jan 1, 1980Paper

Effect of calcium, phosphorus, magnesium, and aluminum on fluoride metabolism in man

Annals of the New York Academy of Sciences
H SpencerM Lender


The studies of the interaction of fluoride with minerals in man have shown that: 1. in contrast to observations made in animals, the high intake of calcium, phosphorus, and magnesium in amounts that can be used in humans did not inhibit the intestinal absorption of fluoride in man; 2. the lack of effect of added calcium, given in divided doses, on the intestinal absorption of fluoride has relevance for the use of a high calcium intake during fluoride therapy for osteoporosis; 3. aluminum as the hydroxide, commonly used as an antacid in clinical medicine, significantly decreases the intestinal absorption of fluoride. This inhibitory effect, in conjunction with the known effects of aluminum-containing antacids in causing calcium loss as a consequence of phosphorus depletion, may contribute to the development of skeletal demineralization.


Aug 1, 1978·Metabolism: Clinical and Experimental·J Jowsey, B L Riggs
Jun 1, 1975·The Journal of Nutrition·H SpencerC Norris
Oct 1, 1974·The Journal of Nutrition·D OsisH Spencer
Aug 1, 1972·Archives of Oral Biology·F BrudevoldY Bakhos
Jun 1, 1973·The Journal of Nutrition·B L O'DellW O Regan
Mar 15, 1974·Clinica Chimica Acta; International Journal of Clinical Chemistry·D OsisH Spencer
Apr 1, 1965·Journal of Pharmaceutical Sciences·J R Mellberg
Dec 1, 1970·The American Journal of Medicine·H SpencerJ Samachson
Dec 1, 1970·The American Journal of Medicine·H SpencerJ Samachson
Jul 1, 1972·The American Journal of Medicine·J JowseyD L Hoffmann
Mar 1, 1970·The Journal of Nutrition·I ZipkinB R Stillings
Dec 1, 1970·The Journal of Nutrition·H SpencerJ Samachson
Apr 1, 1970·Physics in Medicine and Biology·S J Meldrum, B W Watson
Feb 22, 1968·The New England Journal of Medicine·M LotzF C Bartter
Jun 10, 1968·JAMA : the Journal of the American Medical Association·G E Shambaugh, A Petrovic
Apr 1, 1969·The American Journal of Clinical Nutrition·H SpencerJ Samachson
Oct 1, 1965·Proceedings of the Society for Experimental Biology and Medicine·N W Alcock
Aug 1, 1966·Archives of Internal Medicine·R M CassR Terry
Jan 1, 1954·American Journal of Public Health and the Nation's Health·E NETERR M GINO
Nov 10, 1954·The Journal of Nutrition·D A WEDDLE, J C MUHLER
Feb 1, 1957·American Journal of Public Health and the Nation's Health·R L HAYESC L WHITE
Aug 5, 1961·JAMA : the Journal of the American Medical Association·H C HODGE
Feb 1, 1964·Proceedings of the Society for Experimental Biology and Medicine·G K STOOKEYJ C MUHLER
Apr 1, 1964·The Journal of Clinical Investigation·C RICHP IVANOVICH
Feb 1, 1965·Archives of Internal Medicine·D R TAVESD E GARDNER
Aug 1, 1962·The American Journal of Clinical Nutrition·L L RusoffW W Frye
Apr 1, 1951·Journal of Dental Research·F J McCLURE, R C LIKINS

❮ Previous
Next ❯


Mar 1, 1990·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J P DevogelaerF Stein
Jan 1, 1986·Archives of Oral Biology·K Trautner, G Siebert
Feb 1, 1983·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·A Lione
Jul 1, 1995·The British Veterinary Journal·K Dua, A D Care
Dec 22, 2007·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Daniel KrewskiVirginie Rondeau
Mar 1, 1994·Journal of Toxicology and Environmental Health·H W Ahn, E H Jeffery
Nov 2, 2014·The Journal of the American Dental Association·Mark Donaldson, Riva Touger-Decker
Jun 12, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·R A RochaV Devesa
Aug 30, 2008·Journal of Critical Care·Mona MahmoodFatema Ahmed
Jan 11, 2005·The American Journal of Medicine·Michael P WhyteWilliam R Reinus
Jan 8, 2004·Mayo Clinic Proceedings·Robert P Heaney
May 24, 2003·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·Liang Li
Feb 1, 1984·Postgraduate Medicine·T K Jackson, I H Ullrich
Feb 1, 1990·Journal of Dental Research·D G Pendrys, J W Stamm
Dec 1, 1995·The Journal of the American Dental Association·D G Pendrys

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.