PMID: 6940475Jan 1, 1980Paper

Effect of calcium, phosphorus, magnesium, and aluminum on fluoride metabolism in man

Annals of the New York Academy of Sciences
H SpencerM Lender

Abstract

The studies of the interaction of fluoride with minerals in man have shown that: 1. in contrast to observations made in animals, the high intake of calcium, phosphorus, and magnesium in amounts that can be used in humans did not inhibit the intestinal absorption of fluoride in man; 2. the lack of effect of added calcium, given in divided doses, on the intestinal absorption of fluoride has relevance for the use of a high calcium intake during fluoride therapy for osteoporosis; 3. aluminum as the hydroxide, commonly used as an antacid in clinical medicine, significantly decreases the intestinal absorption of fluoride. This inhibitory effect, in conjunction with the known effects of aluminum-containing antacids in causing calcium loss as a consequence of phosphorus depletion, may contribute to the development of skeletal demineralization.

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Citations

Mar 1, 1990·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J P DevogelaerF Stein
Jan 1, 1986·Archives of Oral Biology·K Trautner, G Siebert
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Jul 1, 1995·The British Veterinary Journal·K Dua, A D Care
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Mar 1, 1994·Journal of Toxicology and Environmental Health·H W Ahn, E H Jeffery
Nov 2, 2014·The Journal of the American Dental Association·Mark Donaldson, Riva Touger-Decker
Jun 12, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·R A RochaV Devesa
Aug 30, 2008·Journal of Critical Care·Mona MahmoodFatema Ahmed
Jan 11, 2005·The American Journal of Medicine·Michael P WhyteWilliam R Reinus
Jan 8, 2004·Mayo Clinic Proceedings·Robert P Heaney
May 24, 2003·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·Liang Li
Feb 1, 1984·Postgraduate Medicine·T K Jackson, I H Ullrich
Feb 1, 1990·Journal of Dental Research·D G Pendrys, J W Stamm
Dec 1, 1995·The Journal of the American Dental Association·D G Pendrys

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