Effect of Carapa guianensis Aublet (Andiroba) and Orbignya phalerata (Babassu) in colonic healing in rats

Revista do Colégio Brasileiro de Cirurgiões
Cícero Evandro Soares SilvaIgor Furlan Cella

Abstract

to evaluate the healing effect of the babassu aqueous extract and andiroba oil on open wounds in the cecum of rats. fifty-four Wistar rats were divided into three groups of 18: 1) babassu group with application of aqueous extract of babassu; 2) andiroba group with application of the oil; and 3) control group, with application of saline solution. All procedures were done by gavage. Each group was divided into three subgroups of six animals according to the observation period of 7, 14 or 21 days. From each animal was removed caecum fragment of 1.5cm² diameter. The areas of the lesions were analyzed macroscopically and resected specimens by light microscopy using hematoxylin-eosin and Masson's trichrome. abscess and infection were observed in two aroeira group animals, and in one only hematoma. In relationship to adhesions degree, babassu group had higher incidence of grade II while in the control and aroeira groups predominated adhesions grade I. On microscopic examination on day 7 fibroblast proliferation was greater in aroeira and lower in babassu group (p=0.028). On the 14th day polymorphonuclear were less pronounced in babassu (p=0.007). As for the resistance test of air insufflation, it was observed that in all andiroba grou...Continue Reading

References

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Sep 4, 2013·Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery·Orlando José Dos SantosRennan Abud Pinheiro Santos

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Citations

Jun 9, 2016·Acta Cirúrgica Brasileira·Eros Luiz de SousaDaniel Dantas Ferrarin
May 12, 2016·Acta Cirúrgica Brasileira·Elias AmorimJurandir Ribas-Filho
Jun 2, 2018·Oxidative Medicine and Cellular Longevity·Carlos F Araujo-LimaIsrael Felzenszwalb

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