PMID: 6108865May 1, 1980Paper

Effect of carbidine on dopamine turnover in the rat corpus striatum

Farmakologiia i toksikologiia
L A Malikova, V A Arefolov

Abstract

It has been shown that carbidine increases the level of homovanillic acid (HVA) in the corpus striatum of the rat brain. The changes in HVA level allowed forming a judgement on dopamine turnover. By the intensity of this effect, carbidine proved inferior to typical neuroleptics--triphtazine and ftorfenazin. The antidepressant ftoracizin did not alter HVA level. Carbidine ranks between neuroleptics and antidepressants in terms of the effect on dopamine turnover.

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here