Effect of cardiac resynchronization therapy on left atrial reverse remodeling: role of echocardiographic AV delay optimization

International Journal of Cardiology
Alessandro MalagoliGiovanni Quinto Villani

Abstract

Cardiac resynchronization therapy (CRT) improves left ventricular (LV) function in patients with advanced heart failure (HF) and there are some evidences about beneficial effects also on left atrial (LA) dimension and function. The contribution of atrioventricular delay (AVD) optimization on LA changes has not been evaluated. The purpose of the present study was to further investigate the effect of CRT on LA reverse remodelling and to evaluate the contribution of AVD optimization. From the Cardiology Department of Piacenza Hospital and Modena University Hospital fifty one patients with refractory systolic HF and left bundle branch block were prospectively enrolled before CRT implantation. Patients were 1:1 randomized to either an optimized AVD (AV Opt group) determined by continuous wave Doppler aortic velocity-time integral (VTI) or an empiric AVD of 110 ms (AV Fixed group). Optimal AVD was defined as the AVD that yielded the largest aortic VTI at one of eight tested AV intervals (between 60 and 200 ms). LA volumes and emptying fractions were assessed by two-dimensional echocardiography at baseline and 6 months after CRT. At 6-month follow-up, CRT induced LA reverse remodeling in the whole population (maximal LA volume: 55.8 ±...Continue Reading

References

Oct 8, 1999·The American Journal of Cardiology·S J LesterE Foster
Oct 5, 2001·Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology·J A Salerno-Uriarte, M Tritto
Jun 27, 2002·Journal of the American College of Cardiology·Angelo AuricchioUNKNOWN Pacing Therapies in Congestive Heart Failure (PATH-CHF) Study Group
Nov 29, 2002·The New England Journal of Medicine·Jeroen J BaxMartin J Schalij
May 21, 2004·The New England Journal of Medicine·Michael R BristowUNKNOWN Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure (COMPANION) Investigators
Mar 9, 2005·The New England Journal of Medicine·John G F ClelandUNKNOWN Cardiac Resynchronization-Heart Failure (CARE-HF) Study Investigators
Apr 27, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Navinder S SawhneyMitchell N Faddis
Jan 31, 2006·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Jeffrey E KerlanMitchell N Faddis
Aug 30, 2008·European Heart Journal·Tony StantonJohn J V McMurray
Nov 5, 2008·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·S Serge BaroldBengt Herweg
Nov 7, 2008·Echocardiography·Amit BhanMark J Monaghan
Dec 11, 2008·Pacing and Clinical Electrophysiology : PACE·Claudia YpenburgJeroen J Bax
Jul 14, 2010·International Journal of Cardiology·Xuedong ShenDennis J Esterbrooks

❮ Previous
Next ❯

Citations

Oct 24, 2013·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Guangwei PanMuhuyati Wulasihan
Oct 18, 2015·International Journal of Cardiology·Zhi-Qiang ZhaoGuang-Ping Li
Jun 4, 2013·International Journal of Cardiology·Luca RossiGiovanni Quinto Villani
Feb 4, 2014·International Journal of Cardiology·Giuseppe Mario Calvagna, Salvatore Patanè
Apr 2, 2014·International Journal of Cardiology·M ScaranoS Patanè
Mar 13, 2014·The American Journal of Cardiology·Yidi GeArthur J Moss
Jan 25, 2020·Journal of Clinical Medicine·Ibadete BytyçiMichael Y Henein

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Remodeling

Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.

Related Papers

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Erwan DonalJean-Claude Daubert
Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Hakan AksoyAli Oto
© 2021 Meta ULC. All rights reserved