Effect of Cataract Grade according to Wide-Field Fundus Images on Measurement of Macular Thickness in Cataract Patients

Korean Journal of Ophthalmology : KJO
Mingue KimHyo Myung Kim

Abstract

To investigate the effects of cataract grade based on wide-field fundus imaging on macular thickness measured by spectral domain optical coherence tomography (SD-OCT) and its signal-to-noise ratio (SNR). Two hundred cataract patients (200 eyes) with preoperative measurements by wide-field fundus imaging and macular SD-OCT were enrolled. Cataract severity was graded from 1 to 4 according to the degree of macular obscuring by cataract artifact in fundus photo images. Cataract grade based on wide-field fundus image, the Lens Opacity Classification System III, macular thickness, and SD-OCT SNR were compared. All SD-OCT B-scan images were evaluated to detect errors in retinal layer segmentation. Cataract grade based on wide-field fundus imaging was positively correlated with grade of posterior subcapsular cataracts (rho = 0.486, p < 0.001), but not with nuclear opalescence or cortical cataract using the Lens Opacity Classification System III. Cataract grade was negatively correlated with total macular thickness (rho = -0.509, p < 0.001) and SD-OCT SNR (rho = -0.568, p < 0.001). SD-OCT SNR was positively correlated with total macular thickness (rho = 0.571, p < 0.001). Of 200 eyes, 97 (48.5%) had segmentation errors on SD-OCT. As cat...Continue Reading

References

Sep 1, 1995·Nature Medicine·J G FujimotoE A Swanson
Mar 21, 2000·Current Opinion in Ophthalmology·A Z McColgin, J S Heier
Mar 13, 2001·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·L MastropasquaA Harris
Apr 20, 2004·Journal of Cataract and Refractive Surgery·Conceição L LoboJosé G Cunha-Vaz
Sep 19, 2006·The British Journal of Ophthalmology·M E J van VelthovenF D Verbraak
Jul 11, 2007·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Burkhard von JagowThomas Kohnen
Aug 23, 2008·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Thomas R FribergSteven D Schwartz
Mar 3, 2010·Indian Journal of Ophthalmology·Amitha DomalpallyChristina N Kruse
May 29, 2010·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Sachin S MudvariMathew W MacCumber
Oct 12, 2012·Clinical Ophthalmology·Betül İlkay Sezgin AkçayHuseyin Bayramlar
Feb 16, 2013·JAMA Ophthalmology·Maiko InoueKazuaki Kadonosono
Dec 29, 2013·Current Opinion in Ophthalmology·Christopher Kai-Shun Leung
Jan 7, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Esin Sogutlu SariAdil Kilic
Jan 11, 2014·Investigative Ophthalmology & Visual Science·Maria Cristina SavastanoBenedetto Falsini

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