Effect of Chlorella Ingestion on Oxidative Stress and Fatigue Symptoms in Healthy Men

The Kurume Medical Journal
Hirotaka OkadaKouji Toyomasu

Abstract

We examined the effects of dietary chlorella ingestion on oxidative stress and fatigue symptoms in healthy men under resting and fatigue conditions. We conducted a double-blind, parallel-arm controlled study. Twenty-seven healthy male volunteers (mean age, 35.4±10.4 years) were randomly divided into the chlorella and placebo groups, and received chlorella (6 g/day) and lactose as placebo (7.2 g/day), respectively, for 4 weeks. To simulate mild fatigue, subjects underwent exercise (40% of the heart rate reserve) for 30 minutes. Fatigue was measured using the visual analog scale of fatigue (F-VAS) pre- and post-exercise. Serum antioxidant capacity (AC), malondialdehyde levels, and other indices of oxidative stress were measured pre- and post-exercise. All measurements were repeated after the intervention period and the results were compared with baseline measurements. Under resting conditions, AC significantly increased after the intervention period in the chlorella group, but not in the placebo group. Malondialdehyde levels after the intervention period were significantly lower in the chlorella group than in the placebo group. There were no significant differences in any of the oxidative-stress indices measured pre- and post-exe...Continue Reading

References

Dec 1, 1991·The Journal of Clinical Investigation·J L Witztum, D Steinberg
Jun 1, 1986·Pharmacology, Biochemistry, and Behavior·M FrankenhaeuserG Sedvall
Apr 2, 1996·Proceedings of the National Academy of Sciences of the United States of America·A YoritakaY Mizuno
Jan 1, 1997·Free Radical Biology & Medicine·H BussC C Winterbourn
Dec 9, 1997·Neurobiology of Aging·M A LovellW R Markesbery
Jan 16, 1999·Free Radical Biology & Medicine·L L de ZwartN P Vermeulen
Dec 6, 2005·International Journal of Sport Nutrition and Exercise Metabolism·G W DavisonR A Bell
Aug 25, 2009·Neuroscience Letters·Yuya NakashimaShigeo Ohta
Dec 8, 2009·Amino Acids·Chad M KerksickDarryn S Willoughby
Feb 3, 2011·Rheumatology·Katrine B NorheimRoald Omdal
Oct 4, 2013·Journal of Oleo Science·Taiki MiyazawaTeruo Miyazawa
May 7, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Naoto NoguchiAkira Yamada
May 26, 2016·Biological Psychology·Sanae FukudaHirohiko Kuratsune

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.