PMID: 6412617Mar 1, 1983Paper

Effect of chlorpromazine on pituitary concentrations of gonadotropins and prolactin in the pregnant rat

Annales d'endocrinologie
G Lescoat, Y Chambon

Abstract

Pituitary gonadotropins and prolactin were measured from day 1 (G1) to day 4 (G4) of gestation in control or chlorpromazine injected rats (Img/100 g body weight every 8 hours during 72 hours). Chlorpromazine induced a modification of pituitary gonadotropins and prolactin (decrease in LH from G1 to G4; decrease in FSH from G1 to G3; increase in PRL from G1 to G4). Differed implantation by chlorpromazine seemed to be due to a decrease in pituitary gonadotropins and an increase in pituitary prolactin.

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