PMID: 2116679May 1, 1990Paper

Effect of chronic airflow limitation on resting oxygen consumption

Thorax
C LaniganJ Ponte

Abstract

The work of breathing in patients with severe chronic airflow limitation is increased even at rest but little is known about the magnitude of this increase. Resting oxygen consumption (VO2), carbon dioxide production (VCO2), and respiratory quotient (RQ) were measured in 13 patients with severe chronic airflow limitation (mean FEV1 0.78 1, vital capacity 2.1 1) and compared with those of 13 age, weight, and height matched control subjects. Whereas mean RQ was the same in the two groups (0.82), mean VO2 and VCO2 were higher in the patients (+ 18 ml min-1 and + 15 ml min-1 respectively). When VO2 was standardised for body surface area it was 10.9% higher in the patients (p less than 0.05). If the increased resting VO2 in these patients were solely due to increased activity of the respiratory muscles, it would represent a fourfold increase in the oxygen cost of breathing.

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Citations

Apr 29, 1998·Journal of Cardiopulmonary Rehabilitation·J S Mandak, T R McConnell
Jan 1, 1991·Thorax·J Goldstone, J Moxham
Dec 1, 1993·The American Review of Respiratory Disease·O HugliJ W Fitting
Mar 9, 2013·Advanced Healthcare Materials·John N KheirFrancis X McGowan
Sep 10, 2002·The Australian Journal of Physiotherapy·Edward PontifexDavid Parsons
Oct 26, 2001·The Australian Journal of Physiotherapy·Kate DallimoreBeatrice Tucker
Jul 1, 1992·JPEN. Journal of Parenteral and Enteral Nutrition·A M ScholsW H Saris
Oct 18, 2000·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·A Hedberg, S Rössner
Nov 13, 2019·Journal of Cardiopulmonary Rehabilitation and Prevention·Anelise B MunariAnamaria F Mayer

Related Concepts

Carbon Dioxide
Forced Expiratory Volume Function
Lung
Lung Diseases, Obstructive
Oxygen Consumption
Rest

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