Effect of cigarette smoking on serum alpha-tocopherol and the lipid profile in a Portuguese population

Clinica Chimica Acta; International Journal of Clinical Chemistry
Paula A LopesA M Viegas-Crespo

Abstract

The present study was conducted to determine the effects of cigarette smoking on the levels of serum alpha-tocopherol and on the lipid profile in humans from the Lisbon population. Serum alpha-tocopherol was evaluated by a reverse-phase HPLC method with UV detection. Enzymatic tests were used for the evaluation of the lipid profile. Smokers in general and female smokers in particular had decreased alpha-tocopherol levels when compared with nonsmokers. Smokers had also lower HDL cholesterol (HDL-C) contents, but this difference was statistically significant only for females. Regardless of sex, in smokers, there was a positive correlation between alpha-tocopherol and triglyceride (TG) levels. Cluster analysis showed a sex-independent separation between smokers and nonsmokers. These results suggest a different interaction of these blood parameters in smokers versus nonsmokers that should be further investigated.

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Citations

Jun 3, 2005·International Journal of Impotence Research·G CoronaM Maggi
Dec 13, 2006·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Yin RuixingHuang Jiandong

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