Effect of coffee on motor and sensory function of proximal stomach

Digestive Diseases and Sciences
P J BoekemaA J Smout

Abstract

Some people attribute dyspeptic symptoms to drinking coffee, suggesting that coffee affects one or more functions of the proximal gastrointestinal tract. In a randomized controlled, cross-over, single-blinded study, the effects of coffee on gastric relaxation, gastric wall compliance and sensations, elicited by distension, were investigated in 10 healthy volunteers. Using the barostat technique, volume changes of an intragastric bag were recorded for 20 min after intragastric administration of 280 ml of coffee or water. Then, after deflation, the volume of the bag was increased stepwise every 3 min to assess gastric wall compliance and wall tension. At the end of every volume step, sensations (nausea, pain, and bloating) were scored. During the first 20 min after coffee administration, the volume change of the intragastric bag was larger than after water (P < 0.05). There were no differences in gastric wall compliance, wall tension, or symptom scores. In conclusions, coffee, in comparison with water, enhances the adaptive relaxation of the proximal stomach, but has no effect on its wall compliance, wall tension, or sensory function.

Citations

Mar 31, 2005·Journal of Clinical Gastroenterology·Jan Tack, K J Lee
Feb 26, 2011·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Sam Ryong JeeUNKNOWN Korean Society of Neurogastroenterology and Motility
May 26, 2006·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·S LohsiriwatS Leelakusolvong
Aug 20, 2005·Scandinavian Journal of Gastroenterology·Cornelius E J SlootsErnst J Kuipers
Jul 1, 2016·Comprehensive Reviews in Food Science and Food Safety·L Kirsty PourshahidiJ J Strain

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