Effect of cognitive remediation on gait in sedentary seniors

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Joe VergheseRoee Holtzer

Abstract

Attention and executive functions show strong associations with slow gait and falls in seniors and have been shown to be amenable to cognitive remediation. However, cognitive remediation as a strategy to improve mobility has not been investigated. Using a randomized single-blind control design, 24 sedentary older adults (exercise less than or equal to once weekly and gait velocity <1 m/s) were randomly assigned to an 8-week computerized cognitive remediation program or wait-list. Primary outcome was change in gait velocity during normal pace and "walking while talking" conditions. We also compared the proportion of improvers (velocity change ≥4 cm/s) in each group. The 10 participants who completed cognitive remediation improved gait velocity from baseline during normal walking (68.2 ± 20.0 vs 76.5 ± 17.9 cm/s, p = .05) and walking while talking (36.7 ± 13.5 vs 56.7 ± 20.4 cm/s, p = .002). The 10 intervention participants improved gait velocity over the 8-week intervention both during normal walking (change: 8.2 ± 11.4-1.3 ± 6.8 cm/s, p = .10) and walking while talking (change: 19.9 ± 14.9-2.5 ± 20.1 cm/s, p = .05) compared with the 10 control participants. Six intervention participants were improvers on normal pace walking com...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Jan 1, 1990·Annual Review of Neuroscience·M I Posner, S E Petersen
Mar 1, 1997·American Journal of Public Health·J A LangloisR B Wallace
Oct 18, 2000·Biological Psychology·T A Salthouse
May 2, 2002·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Maria Antoinette Fiatarone Singh
Oct 18, 2002·Journal of the American Geriatrics Society·Joe VergheseRichard Lipton
Nov 13, 2002·JAMA : the Journal of the American Medical Association·Karlene BallUNKNOWN Advanced Cognitive Training for Independent and Vital Elderly Study Group
Jun 20, 2003·The New England Journal of Medicine·Joe VergheseHerman Buschke
Aug 7, 2003·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Anne B NewmanUNKNOWN Health ABC Collaborative Research Group
Sep 27, 2003·Journal of the American Geriatrics Society·Richard B LiptonHerman Buschke
Nov 26, 2003·Archives of Internal Medicine·Jennifer S BrachAndrea M Kriska
Apr 6, 2006·Neuropsychology·Roee HoltzerRichard B Lipton
May 4, 2006·JAMA : the Journal of the American Medical Association·Anne B NewmanTamara B Harris
Oct 19, 2006·Progress in Brain Research·Henry W MahnckeMichael M Merzenich
Dec 21, 2006·JAMA : the Journal of the American Medical Association·Sherry L WillisUNKNOWN ACTIVE Study Group
Jan 9, 2007·Archives of Physical Medicine and Rehabilitation·Joe VergheseMarco Pahor
Jan 24, 2007·Journal of Neurology, Neurosurgery, and Psychiatry·Joe VergheseXiaonan Xue
Jun 1, 2007·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Jason S Haukoos, Craig D Newgard
Aug 19, 2007·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Marco InzitariUNKNOWN ILSA Working Group
Sep 6, 2007·Neuropsychology·Roee HoltzerJoe Verghese
Nov 17, 2007·Journal of Anesthesia·Tamie Arai, Sumio Hoka
Feb 13, 2008·Journal of the American Geriatrics Society·Ron Ben-ItzhakJeffrey M Hausdorff
Apr 17, 2008·Behavioral Sleep Medicine·Iris HaimovYael Horowitz
Apr 8, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Joe VergheseCuiling Wang
May 12, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Teresa Liu-AmbroseChun Liang Hsu
Jun 19, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Ihab HajjarLewis A Lipsitz
Sep 3, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·E Fuller-ThomsonM Minkler
Nov 6, 2009·Gait & Posture·Jennifer S BrachJoe Verghese
Dec 9, 2009·Gait & Posture·Sandra G Brauer, Meg E Morris
Apr 27, 2010·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Verena KlusmannFernando C Dimeo

❮ Previous
Next ❯

Citations

Feb 2, 2013·Experimental Brain Research·Galit Yogev-SeligmannJeffrey M Hausdorff
Oct 21, 2011·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Hilaire J ThompsonBlaine Reeder
Feb 15, 2011·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Andrea L RossoYvonne L Michael
Apr 19, 2011·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Christopher R CarpenterDouglas K Miller
May 20, 2011·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Roee HoltzerJoe Verghese
Jul 12, 2013·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Andrea L RossoCaterina Rosano
Nov 29, 2013·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Roee HoltzerJoe Verghese
Nov 30, 2011·Journal of Geriatric Physical Therapy·Mooyeon Oh-ParkJoe Verghese
May 18, 2013·Clinical Interventions in Aging·A PerrochonA Berthoz
Feb 8, 2014·Neurophysiologie clinique = Clinical neurophysiology·L Borel, B Alescio-Lautier
May 8, 2014·Aging Clinical and Experimental Research·Jean-Paul Steinmetz, Carine Federspiel
Oct 23, 2012·Accident; Analysis and Prevention·Lesley A RossKarlene Ball
Jan 14, 2012·Journal of the American Geriatrics Society·Annadora J Bruce-KellerJeffrey N Keller
Apr 18, 2013·Journal of the American Geriatrics Society·Neelesh K NadkarniJessie M Van Swearingen
Jun 26, 2013·Journal of the American Geriatrics Society·Michele L CallisayaVelandai K Srikanth
Aug 9, 2011·Annals of Neurology·Lydia Rolita, Joe Verghese
Nov 1, 2012·Journal of the American Geriatrics Society·Manuel Montero-OdassoJeffrey M Hausdorff
Feb 14, 2014·Human Brain Mapping·Helena M BlumenJoe Verghese
May 27, 2015·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Michele L CallisayaVelandai K Srikanth
May 21, 2014·NeuroImage·Niousha BolandzadehCaterina Rosano
May 12, 2015·Journal of the American Medical Directors Association·Jean Woo
Nov 7, 2013·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Renae L Smith-RayDonald Hedeker
Mar 26, 2013·Maturitas·Anne Felicia AmbroseJeffrey M Hausdorff
Jun 1, 2016·Maturitas·Jason A CohenJessica L Zwerling
Jun 22, 2016·The Quarterly Journal of Experimental Psychology : QJEP·Becky I HaynesDavid Bunce
Oct 25, 2016·Journal of the Neurological Sciences·Manuel E HernandezRobert W Motl
Oct 3, 2014·Health Education & Behavior : the Official Publication of the Society for Public Health Education·Renae L Smith-RaySusan L Hughes
Dec 3, 2016·Neurorehabilitation and Neural Repair·Courtney C WaltonSimon J G Lewis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Expert Review of Neurotherapeutics
Orit Segev-JacubovskiJeffrey M Hausdorff
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Karen Z H LiP A McKinley
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Talia HermanJeffrey M Hausdorff
© 2021 Meta ULC. All rights reserved