PMID: 44699Nov 1, 1979

Effect of colony type and pH on surface charge and hydrophobicity of Neisseria gonorrhoeae

Infection and Immunity
K E MagnussonS Normark

Abstract

The effect of colonial variation and growth at pH 7.2 or pH 6.0 on the surface properties of Neisseria gonorrhoeae was assessed by the use of two-phase partitioning and hydrophobic interaction chromatography. Cells grown at pH 7.2 tended to be both hydrophobic and to possess a slight negative charge. Growth at pH 6.0 appeared to decrease hydrophobicity and to increase the negative surface charge. Possession of a series of outer membrane proteins, termed the colony opacity-associated proteins, did not appear to significantly affect charge or hydrophobicity. Piliated cells tended to have a higher negative charge than nonpiliated variants. They also tended to be less hydrophobic at pH 7.2, but became more hydrophobic at pH 6.0. The implications of these findings are discussed.

References

Jun 1, 1987·Biotechnology and Bioengineering·H H WangJ P Hsu

Related Concepts

Bacterial Proteins
Resting Potentials
Bacterial Pilus
Cell Surface Proteins
Neisseria gonorrhoeae
Hydrogen-Ion Concentration
Variation (Genetics)

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