PMID: 1202703Nov 1, 1975Paper

Effect of combined application of carboxylin and sodium citrate on the restoration of blood proteins under conditions of experimental anemia

Ukrainskiĭ biokhimicheskiĭ zhurnal
M F Guly, L I Holubeva

Abstract

Under the effect of combined application of "carboxylin"--the preparation stimulating the processes of CO2 fixation in the tissues and sodium citrate--one of the most important intermediates of the cycle of citric acid, the processes of the erythrocytic and protein composition restoration in the peripheral blood were studied under conditions of posthemorrhagic anemia in rats. It is established that under the effect of combined application of "carboxylin" with sodium citrate there is observed rapid normalization of peripheral blood indexes--erythrocytes, hemoglobin, hematocrit number, total proteins, albumin and globulins of blood serum. All mentioned evidences for a stimulating effect of the given preparations on the biosynthetic processes in the organism and for possibility of blood regeneration acceleration under conditions of posthemorrhagic anemia.

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