PMID: 7992461Jan 1, 1994Paper

Effect of combined supplementation of magnesium oxide and pyridoxine in calcium-oxalate stone formers

Urological Research
V RattanR Nath

Abstract

A combined supplement of magnesium oxide (300 mg/day) and pyridoxine.HCl (10 mg/day) was given p.o. to 16 recurrent calcium oxalate (CaOx) stone formers, and its therapeutic efficacy was biochemically evaluated by measuring various parameters of blood (Na, K, Mg, urea, creatinine, calcium, phosphate, uric acid, alanine transaminase, aspartate transaminase and alkaline phosphatase) and urine (volume, pH, creatinine, Na, K, Mg, uric acid, calcium, phosphate, oxalate and citrate) at 0, 30, 60, 90 and 120 days of treatment. Serum Mg significantly (P < 0.01) increased after 30 days of treatment and remained constant thereafter while other blood parameters were unaltered. Combined treatment led to a significant increase in the urinary excretion of Mg and citrate over pretreatment values while oxalate excretion showed a gradual and significant decline during the therapy. The results confirmed the efficacy of MgO-pyridoxine supplementation in terms of changes in urinary excretion of lithogenic and inhibitory components, leading to a significant (P < 0.01) decrease in CaOx risk index from 0.09 +/- 0.04 at 0 day to 0.05 +/- 0.02 after 120 days of treatment.

References

May 1, 1979·Metabolism: Clinical and Experimental·E J Will, O L Bijvoet
Jan 29, 1976·The New England Journal of Medicine·W G RobertsonB E Nordin
Apr 1, 1992·The Journal of Clinical Endocrinology and Metabolism·M Menon, H Koul
Apr 1, 1991·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·C J Danpure
Dec 15, 1989·Annals of Internal Medicine·J UribarriH J Carroll
Oct 1, 1974·The Journal of Urology·E L Prien, S F Gershoff
Jan 1, 1972·Clinica Chimica Acta; International Journal of Clinical Chemistry·A Hodgkinson, A Williams
Feb 1, 1970·Clinical Science·D A Gibbs, R W Watts
Jan 1, 1971·The Journal of Urology·I MelnickJ F Burch
Jan 1, 1982·Annals of Nutrition & Metabolism·M S MurthyR Nath
Jul 15, 1982·Clinica Chimica Acta; International Journal of Clinical Chemistry·H G Tiselius
Nov 1, 1963·Transactions of the New York Academy of Sciences·S NATELSON

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Citations

Dec 10, 2009·Urological Research·Y M Fazil MarickarAdarsh Vijay
Jan 11, 2000·Urology·B F SchwartzM L Stoller
May 8, 2001·Journal of Endourology·B F SchwartzM L Stoller
Aug 30, 2008·International Journal of Urology : Official Journal of the Japanese Urological Association·Yaovalak TeerajetgulYoshihide Ogawa
Jul 3, 2004·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Sonja Lewandowski, Allen L Rodgers
Feb 7, 2001·The Journal of Urology·M Liebman, G Costa
Apr 25, 2000·The Urologic Clinics of North America·D G Assimos, R P Holmes
Nov 1, 2016·Scientific Reports·Kedsarin Fong-Ngern, Visith Thongboonkerd
Nov 22, 2001·Journal of Feline Medicine and Surgery·K M ByrneL Brownlee
Sep 1, 1995·The Journal of Urology·H G TiseliusM A Nilsson
Jul 5, 2017·Urolithiasis·Pietro Manuel FerraroGary C Curhan
Apr 15, 1999·Journal of the American Society of Nephrology : JASN·G C CurhanM J Stampfer
Jul 14, 2021·Journal of Endourology·Mantu GuptaWilliam Atallah

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