PMID: 9534749Apr 16, 1998Paper

Effect of concurrent lower genital tract infections on cervical cancer screening

Genitourinary Medicine
Jane R Schwebke, M E Zajackowski

Abstract

Although women attending STD clinics are at high risk for cervical cancer, most STD programmes do not include Papanicolaou (Pap) smears in their routine screening procedures. Concerns regarding reliability of this test in a population with a high rate of active infection are often raised. The objective of this study was to analyse the associations between STD diagnosis/clinical syndromes and unsatisfactory and abnormal Pap smears. Retrospective analysis of Pap results and medical records from women attending an inner city STD programme. Of the 1202 patients analysed, 3.2% had squamous intraepithelial lesions (SIL) and 3.5% had smears which were unsatisfactory because of the thickness of the specimen. There were no associations between STD diagnoses and SIL; however, the presence of cervical inflammation was significantly associated with SIL. Pap smears which were unsatisfactory because they were too thick were also associated with the clinical finding of cervical inflammation. The presence of active infection did not preclude the detection of SIL on Pap smears. The percentage of unsatisfactory smears resulting from inflammation was low.

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Citations

Oct 20, 2007·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·B GoswamiA Sharma
Jan 30, 1999·Sexually Transmitted Infections·S K Edwards, C Sonnex
Apr 5, 2001·Sexually Transmitted Infections·J D WilsonUNKNOWN British Co-operative Clinical Group
Oct 4, 2012·Cytokine & Growth Factor Reviews·Jermaine I G Coward, Hagen Kulbe
Aug 9, 2007·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Beatriz M Tavares-MurtaEddie Fernando C Murta
Feb 14, 2006·Journal of Pediatric and Adolescent Gynecology·Khalil G GhanemLauri E Markowitz
Jul 23, 2016·Journal of Immunology Research·Anthonio O AdefuyeArieh A Katz
Feb 11, 2015·Oncology Letters·José Veríssimo FernandesJosélio Maria Galvão DE Araújo
Mar 14, 2000·Cytopathology : Official Journal of the British Society for Clinical Cytology·J HollingworthD Ireland

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