Effect of context on respiratory rate measurement in identifying non-severe pneumonia in African children.

Tropical Medicine & International Health : TM & IH
Florida MuroHugh Reyburn

Abstract

Cough or difficult breathing and an increased respiratory rate for their age are the commonest indications for outpatient antibiotic treatment in African children. We aimed to determine whether respiratory rate was likely to be transiently raised by a number of contextual factors in a busy clinic leading to inaccurate diagnosis. Respiratory rates were recorded in children aged 2-59 months presenting with cough or difficulty breathing to one of the two busy outpatient clinics and then repeated at 10-min intervals over 1 h in a quiet setting. One hundred and sixty-seven children were enrolled with a mean age of 7.1 (SD ± 2.9) months in infants and 27.6 (SD ± 12.8) months in children aged 12-59 months. The mean respiratory rate declined from 42.3 and 33.6 breaths per minute (bpm) in the clinic to 39.1 and 32.6 bpm after 10 min in a quiet room and to 39.2 and 30.7 bpm (P < 0.001) after 60 min in younger and older children, respectively. This resulted in 11/13 (85%) infants and 2/15 (13%) older children being misclassified with non-severe pneumonia. In a random effects linear regression model, the variability in respiratory rate within children (42%) was almost as much as the variability between children (58%). Changing the respirat...Continue Reading

References

Feb 1, 1992·The Pediatric Infectious Disease Journal·E K MulhollandS Gove
Dec 1, 1989·The Pediatric Infectious Disease Journal·F ShannP Poore
Nov 1, 1993·Transactions of the Royal Society of Tropical Medicine and Hygiene·T J O'DempseyB M Greenwood
Jun 12, 2002·Transactions of the Royal Society of Tropical Medicine and Hygiene·E KahigwaC Menendez
Sep 26, 2006·Lancet·Tessa WardlawElizabeth Mason
Feb 26, 2008·Bulletin of the World Health Organization·Hugh ReyburnRaimos Olomi
Jun 12, 2008·Bulletin of the World Health Organization·Igor RudanHarry Campbell
Nov 21, 2008·Transactions of the Royal Society of Tropical Medicine and Hygiene·Chris Drakeley, Hugh Reyburn
Mar 28, 2009·The Lancet Infectious Diseases·Rami SubhiUNKNOWN Hypoxaemia in Developing Countries Study Group
Dec 25, 2009·The Pediatric Infectious Disease Journal·Sonal ShahMark I Neuman
Mar 30, 2010·Lancet·Igor RudanUNKNOWN WHO/UNICEF's Child Health Epidemiology Reference Group (CHERG)
Apr 22, 2011·Malaria Journal·Peter WinskillMatthew J Kirby
Oct 8, 2011·PLoS Medicine·Igor RudanUNKNOWN WHO/CHNRI Expert Group on Childhood Pneumonia

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Citations

Nov 20, 2016·Tropical Medicine & International Health : TM & IH·Florida MuroJim Todd
Feb 10, 2017·PloS One·Sivani JonnalagaddaDavidson H Hamer
Nov 14, 2017·BMC Medicine·Timothy TutiUNKNOWN Clinical Information Network Author Group
Oct 12, 2018·Tropical Medicine & International Health : TM & IH·Coleman KishamaweLeonard E G Mboera
Nov 27, 2019·The American Journal of Tropical Medicine and Hygiene·Daniel HelldénTobias Alfvén
Oct 12, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Eric D McCollum, Amy Sarah Ginsburg
Jul 13, 2019·The European Respiratory Journal·Cristina Ardura-Garcia, Claudia E Kuehni
Jun 5, 2020·ERJ Open Research·Jennifer L LenahanAmy Sarah Ginsburg
May 6, 2021·International Journal of Environmental Research and Public Health·Samweli Faraja MiyayoTang-Huang Lin

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