Effect of deep inspiration on airway caliber in children with asthma

Pediatric Pulmonology
Dagnachew AssefaAllen J Dozor

Abstract

The objective of this study was to assess the effect of deep inspiration (DI) on airway caliber in school-age children with asthma. Thirty children with asthma (10 from each group of mild, moderate, and severe persistent asthma as defined by the National Asthma Education and Prevention Program guidelines of the National Heart, Lung, and Blood Institute) were enrolled, and their results were compared to those obtained in 7 healthy children. Subjects performed a partial expiratory flow volume curve (P) initiated from approximately 70% of vital capacity (VC) followed by a maximal expiratory flow volume (M) maneuver begun from total lung capacity (TLC). The M/P ratio at 30% of the VC (M/P30) was calculated. Specific airway conductance (sGaw) was measured before and immediately after DI, using standard techniques. Differences in M/P30 and sGaw ratios between asthma and control groups were compared with Student's unpaired t-tests. One-way ANOVA was used to compare the effect of DI on M/P30 and sGaw ratios among the various asthma severity groups. The M/P30 ratio (mean +/- 1 SD) was significantly lower in children with moderate and severe persistent asthma (0.73 +/- 0.21 and 0.72 +/- 0.1, respectively) than in healthy controls (1.69 +...Continue Reading

References

Feb 1, 1978·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·J Mead
Jul 1, 1977·The Journal of Allergy and Clinical Immunology·J E FishD W Cugell
Jun 1, 1977·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·A L MansellH Levison
Mar 1, 1976·Journal of Applied Physiology·N NeuburgerK Kruger
Jun 1, 1976·Journal of Applied Physiology·A ZapletalM Samanek
Jan 1, 1992·Journal of Applied Physiology·H JiangN L Stephens
Apr 1, 1990·The American Review of Respiratory Disease·M B HershensonA R Stark
May 1, 1989·Journal of Applied Physiology·L B PlissR H Ingram
Jan 1, 1986·Journal of Applied Physiology·S K KongN L Stephens
Nov 1, 1985·Journal of Applied Physiology·C B BurnsR H Ingram
Dec 1, 1970·Journal of Applied Physiology·J T SharpJ Danon
Sep 1, 1968·Journal of Applied Physiology·H F Froeb, J Mead
May 1, 1981·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·J E FishV I Peterman
Nov 1, 1995·The Journal of Clinical Investigation·G SklootA Togias
Jan 1, 1995·Journal of Applied Physiology·C PapastamelosJ L Allen
Jan 1, 1996·American Journal of Respiratory and Critical Care Medicine·P T Macklem
Aug 1, 1996·Journal of Applied Physiology·R PellegrinoJ R Rodarte
Dec 1, 1996·Journal of Applied Physiology·J J FredbergG C Sieck
May 1, 1997·American Journal of Respiratory and Critical Care Medicine·M J HaydenP N LeSouëf
Apr 6, 2000·Journal of Applied Physiology·M MilaneseV Brusasco
May 10, 2002·Pediatric Pulmonology·François MarchalCatherine Moreau-Colson

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Citations

Aug 8, 2009·Respirology : Official Journal of the Asian Pacific Society of Respirology·Thomas K AnsellPeter K McFawn
Mar 3, 2011·Respirology : Official Journal of the Asian Pacific Society of Respirology·Bruno MahutNicole Beydon
Jun 7, 2005·American Journal of Physiology. Lung Cellular and Molecular Physiology·Lu WangThomas M Murphy
Jun 19, 2009·American Journal of Respiratory and Critical Care Medicine·Helen K ReddelUNKNOWN American Thoracic Society/European Respiratory Society Task Force on Asthma Control and Exacerbations
Feb 22, 2008·Pediatric Research·François MarchalYen Thi Nguyen
Dec 26, 2006·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·C Schweitzer, F Marchal
Oct 20, 2006·Respiratory Medicine·Nicola ScichiloneVincenzo Bellia
Feb 2, 2006·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Tina M EvansJennifer M Baumann
Apr 2, 2008·Medicine and Science in Sports and Exercise·Maria R BonsignoreGiuseppe Morici
Oct 20, 2005·The Cochrane Database of Systematic Reviews·J YorkeC Shuldham
Jul 30, 2021·ERJ Open Research·Michael Fayon, Fabien Beaufils

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