Effect of deoxynivalenol on growth performance, histological morphology, anti-oxidative ability and immune response of juvenile Pacific white shrimp, Litopenaeus vannamei

Fish & Shellfish Immunology
Shiwei XieLi-Xia Tian

Abstract

A 5-weeks experiment was conducted to evaluate the effect of deoxynivalenol on growth performance, histological morphology, anti-oxidative ability and immune capacity of Litopenaeus vannamei. White shrimp (mean initial weight 1.02 g) were fed seven isonitrogenous diets, Diet 1 as the control, Diet 2-4 was supplemented with grade levels (250, 500 and 1000 μg kg-1) of deoxynivalenol (DON), Diet 5-7 were formulated to contain graded levels of contaminated wheat flour. Each diet was assigned to four tanks (30 shrimp). The weight gain was decreased with the increasing dietary DON levels, survival was lower in shrimp fed high levels of DON-contaminated wheat flour (P < 0.05). Feed intake and feed conversion ratio did not show any difference among all the groups. After 4 h hypoxia stress, survival of shrimp was decreased in shrimp fed high levels of DON-contaminated wheat flour (P < 0.05). Total antioxidant capacity in hepatopancreas was higher in shrimp fed the control diet, glutathione S-transferase (GST) activity were higher in shrimp fed the Diet 3 and Diet 6, superoxide dismutase (SOD) activity was higher in shrimp fed the highest dietary DON (Diet 4), while the gene expression of SOD and GPx were lower in shrimp fed the Diet 3-7...Continue Reading

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