PMID: 3215329Sep 1, 1988Paper

Effect of destruction of the hypothalamic suprachiasmatic nuclei on the dynamics of swimming and haloperidol-induced catalepsy in rats

Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova
E B ArushanianE V Shchetinin

Abstract

After bilateral destruction of suprachiasmatic nuclei, with adjacent hypothalamic structures remaining intact, the number of rest-activity cycles during forced swimming as well as short waves with 2-4-min periodicity in haloperidol catalepsy, were increased in rats. The circadian rhythm became disorganized. Suprachiasmatic nuclei seem to be able to delay and synchronize the fluctuations with short periods in motor activity.

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