Effect of dexamethasone on testicular enzymes of the Embden-Meyerhof and pentose-phosphate pathways

International Journal of Andrology
H M ValivullahP Govindarajulu


The influence of dexamethasone on the specific activities of testicular enzymes involved in the Embden-Meyerhof and pentose-phosphate pathways was studied in pre-pubertal, pubertal and adult rats. All of the enzymes showed a decrease in specific activity after dexamethasone treatment, an effect which was most drastic in pre-pubertal animals. After cessation of treatment, the specific activity of all the enzymes reverted to normal levels, except for glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in the pre-pubertal group.


Aug 1, 1977·The Journal of Clinical Endocrinology and Metabolism·A G SmalsT J Benraad
Sep 1, 1977·The Journal of Clinical Endocrinology and Metabolism·J P LutonH Bricaire
Jul 1, 1979·Acta Endocrinologica·T J McKennaD Rabin
Mar 1, 1972·Journal of Reproduction and Fertility·A SosaA Rosado
Feb 1, 1983·International Journal of Andrology·H M ValivullahP Govindarajulu

Related Concepts

Pentose Phosphate Pathway
Enzymes, antithrombotic
August Rats
Glucose, (beta-D)-Isomer
Glucosephosphate Dehydrogenase
Glucose-6-phosphate Dehydrogenase Measurement, Quantitative

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