Effect of dexmedetomidine added to ropivicaine for caudal anesthesia in patients undergoing hemorrhoidectomy: A prospective randomized controlled trial

Medicine
Deming XuHengfei Luan

Abstract

To assess the effect of dexmedetomidine added to ropivaccaine on the onset and duration of sensory block, as well as postoperative analgesia during caudal anesthesia in patients undergoing hemorrhoidectomy. Fifty adult patients scheduled for hemorrhoidectomy were divided into 2 groups. The group R received caudal anesthesia using 18 mL 0.3% ropivacaine plus 2 mL normal saline. The group RD received 18 mL 0.3% ropivacaine plus 2 mL 1 μg/kg dexmedetomidine. Heart rate, mean blood pressure, onset time and duration of sensory block, and duration of analgesia were observed. The onset time of sensory block was shortened (9.2 ± 1.3 vs 7.2 ± 1.2), and the duration of sensory block (3.0 ± 0.7 vs 3.8 ± 0.8) and duration of analgesia (3.9 ± 0.7 vs 5.3 ± 0.8) were prolonged in group RD compared with group R (P < .05). The heart rate and the mean blood pressure were also lower in the group RD compared with group R at each observation time points, except the baseline (P < .05). No bradycardia or hypotension was reported. Dexmedetomidine as an adjuvant to ropivacaine prolonged the duration of caudal block and improved postoperative analgesia without significant side effects in adult patients undergoing hemorrhoidectomy.

References

Oct 5, 2006·Current Opinion in Anaesthesiology·J S Gabriel, V Gordin
Oct 5, 2010·Anesthesia and Analgesia·Aliye EsmaogluCemil Yildirim Turk
Aug 10, 2011·Paediatric Anaesthesia·Martin Jöhr, Thomas M Berger
Aug 25, 2015·Revista brasileira de anestesiologia·Pinar ErgenogluAnis Aribogan
May 24, 2016·Anesthesia, Essays and Researches·Vigya GoyalKrishnaprabha Radhakrishnan
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Dec 2, 2017·Journal of Clinical Pharmacy and Therapeutics·E KorakiA Trikoupi

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Citations

Aug 28, 2020·Journal of Clinical Medicine·Mohamed MahmoudKeira P Mason

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Methods Mentioned

BETA
sedation

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SPSS

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