Effect of dexmedetomidine as an adjuvant to levobupivacaine in supraclavicular brachial plexus block: A randomized double-blind prospective study

Journal of Anaesthesiology, Clinical Pharmacology
Haramritpal KaurShobha Aggarwal

Abstract

Regional anesthesia is a recommended technique for upper and lower limb surgeries with better postoperative profile. In this, randomized, double-blind study, we evaluated the effectiveness of the addition of dexmedetomidine to varying concentration of levobupivacaine for supra clavicular brachial plexus block. After obtaining ethical Committee approval, a double-blind, randomized prospective clinical study was conducted on 90 American Society of Anesthesiologist Grade I and II patients in the age group of 18-55 years, divided randomly into two groups: Group A received 40 ml of solution containing 30 ml 0.5% levobupivacaine and 10 ml 1% lignocaine and group B received 40 ml of solution containing 30 ml 0.25% levobupivacaine and 10 ml 1% lignocaine with dexmedetomidine 1 microg/kg for supraclavicular brachial plexus block. Besides effectiveness, other parameters observed were: duration of sensory blockade; onset and duration of motor blockade; duration of postoperative analgesia; and patient satisfaction score. Onset of sensory and motor blockade was 7.6 ± 1.006 min and 8.3 ± 0.877 min in group A, while it was 6.96 ± 1.077 min an 7.6 ± 1.1 min in group B, respectively. The difference was statistically significant (P < 0.05). Dura...Continue Reading

References

May 1, 1964·Anesthesiology·A P WINNIE, V J COLLINS
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Jul 19, 2008·Anesthesia and Analgesia·Tatsushi YoshitomiTakuya Miyawaki
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Jun 1, 2012·Current Therapeutic Research, Clinical and Experimental·Kenan KaygusuzCaner Mimaroglu

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Citations

Aug 11, 2018·European Journal of Anaesthesiology·Alexander SchnabelChristine H Meyer-Frießem
Oct 6, 2020·Journal of Anaesthesiology, Clinical Pharmacology·Nidhi SinghSuneet Kathuria

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Methods Mentioned

BETA
sedation

Software Mentioned

Statistical Package for Social Sciences

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