PMID: 2484355Sep 1, 1988Paper

Effect of diet on the response in rats to lead acetate given orally or in the drinking water

Biological Trace Element Research
G O Korsrud, J B Meldrum

Abstract

Liver lead levels were higher for rats that were orally dosed with 100 mg lead acetate/kg body wt and fed a semipurified diet than those fed a pelleted diet. The activities of delta-aminolevulinic acid dehydratase in blood were decreased in the group given 10 micrograms lead acetate/mL in their drinking water and fed the semipurified diet, but not in the blood from the group treated with lead and fed the pelleted diet. The levels of glutathione in the liver decreased in response to lead acetate in the drinking water of rats fed the semipurified diet, but not in the livers from the group fed the pelleted diet and treated with lead. The levels of lead in the kidneys were higher in the group given lead acetate in their drinking water and fed the semipurified diet than in the lead treated group fed the pelleted diet. Rats dosed orally with lead or given lead in the drinking water and fed the semipurified diet were more sensitive to lead treatment than those fed the pelleted diet.

References

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Citations

Aug 7, 2012·Archives of Environmental Contamination and Toxicology·Luciane Rosa FeksaTatiana Emanuelli
Oct 21, 2010·Biological Trace Element Research·Ahmed E Abdel-MoneimSaleh Al-Quraishy
Nov 21, 2000·Free Radical Biology & Medicine·H Gurer, N Ercal
Nov 21, 2009·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Tatiana Wannmacher LepperLuciane Rosa Feksa
Apr 12, 2014·Environmental Research·Silvia EspínAntonio Juan García-Fernández
May 1, 1992·British Journal of Industrial Medicine·E GubéranJ Puissant
Dec 24, 1997·Occupational and Environmental Medicine·B A RixE Lynge
Apr 1, 1994·Irish Journal of Medical Science·P O'ReillyJ Clancy
May 2, 2001·Nutrition Reviews·C Ballew, B Bowman

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