PMID: 2105184Feb 1, 1990Paper

Effect of dietary protein and amino acids on immune function

Critical Care Medicine
J M DalyM D Liberman

Abstract

The normal immune system has local and systemic components which are influenced by a variety of alterations. Impaired host immunity is associated with neoplasia, protein calorie malnutrition, and the administration of immunosuppressive drugs. It is well accepted that protein calorie malnutrition impairs host immunity with particular detrimental effects on the T-cell system, resulting in increased opportunistic infection and increased morbidity and mortality in hospitalized patients. Individual nutrient substrates may also have a major influence on the immune system. Individual amino acids are often described as essential, based on requirements for optimal growth and maintenance of positive N balance. Arginine has been demonstrated to be essential to the traumatized host and may have tissue-specific properties which influence components of the immune system. Thus, arginine may be of value in clinical situations where the immune system is compromised. In a series of experiments in normal animals, arginine was demonstrated to enhance cellular immune mechanisms, in particular T-cell function. It also has a marked immunopreserving effect in the face of immunosuppression induced by protein malnutrition and increases in tumor burden. ...Continue Reading

Citations

Mar 1, 1993·World Journal of Surgery·J Yee, N V Christou
Oct 1, 1993·Physiology & Behavior·L MilakofskyW H Vogel
Mar 15, 2003·Clinics in Plastic Surgery·John L BurnsLinda G Phillips
May 20, 1998·Nutrition·R M BeattieT T MacDonald
Feb 20, 2004·Journal of Sports Sciences·Michael GleesonBente K Pedersen
Apr 1, 1992·Acta Anaesthesiologica Scandinavica·M Salo
Sep 27, 2012·American Journal of Physiology. Endocrinology and Metabolism·Yvette C LuikingNicolaas E P Deutz
Jan 8, 2010·Journal of Cardiovascular Pharmacology and Therapeutics·Kevin S HeffernanEshan A Patvardhan
May 16, 2006·Critical Care : the Official Journal of the Critical Care Forum·Suzana M LoboGeni S Cunrath
Oct 27, 2006·Nutrition Reviews·Harri Hemilä
Sep 28, 2004·Indian Journal of Pediatrics·Archana B Patel, Ambarish M Athavale
Aug 24, 2005·The British Journal of Nutrition·Yan Chun ManKo Kam Kei
Dec 16, 1998·The British Journal of Nutrition·B KoletzkoS Strobel
Oct 31, 2007·Clinics in Plastic Surgery·Wesley T MyersLinda G Phillips
Jan 1, 1994·Clinics in Dermatology·A Barbul, W A Purtill
Sep 11, 2004·Critical Care Nursing Clinics of North America·Judy T VergerKathryn E Roberts
Oct 10, 2002·Infectious Disease Clinics of North America·John R Ebright, Barbara Pieper
Jan 1, 1995·The Veterinary Clinics of North America. Small Animal Practice·S W Crane
Apr 28, 2009·Pharmacology & Therapeutics·Toshihiro DohiNorimitsu Morioka
Oct 16, 2004·Critical Care Medicine·Yvette C LuikingNicolaas E Deutz
Jan 1, 1994·Archives of Gerontology and Geriatrics·E MocchegianiN Fabris
Dec 8, 2016·Diseases of the Colon and Rectum·Lucas W ThornbladeDavid R Flum
May 1, 1997·The Journal of Trauma·C MendezR V Maier
Jul 10, 2014·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Petra Pavlickova AimovaZdenek Zadak
Nov 1, 1995·The British Journal of Surgery·A C WindsorJ V Reynolds
Oct 6, 2009·The Journal of Veterinary Medical Science·Zhixiong HeZhiliang Tan

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