Effect of donor variables on yield in single donor plateletpheresis by continuous flow cell separator

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
R ChaudharyPratul Sinha

Abstract

The quality of single donor platelets (SDPs) in terms of yield influences platelet recovery in the recipient. Various donor factors such as pre-donation platelet count and hemoglobin (Hb) concentration affect the platelet yield. We studied the influence of pre-donation donor clinical and laboratory factors such as gender, age, weight of the donor, platelet count and Hb on the platelet yield. A total of 94 plateletpheresis procedures performed on continuous flow cell separator (CS3000, Baxter Healthcare, Round Lake, IL, USA) were evaluated for platelet yield. A relationship between pre-donation donor variables and yield of platelets was studied using the Pearson correlation. The mean platelet yield was 2.8+/-0.73x10(11). While a direct relationship was observed between pre-donation platelet count and yield (r=0.50, p<0.001), no such correlation was noticed with donor Hb concentration (r=-0.10, p>0.005). Similarly, no correlation was observed between gender (r=0.05), age (r=0.11) and weight (r=0.18) of the donor with yield. Optimization of platelet yield, which is influenced by pre-donation platelet count, is an emerging issue in blood transfusion services. Identification of such factors may help in selecting donors to obtain hig...Continue Reading

References

Apr 18, 2003·Archives of Medical Research·Susana Guerrero-RiveraJavier Pizzuto-Chávez

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Citations

May 7, 2013·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Laila NomaniMeena Sidhu
Mar 1, 2012·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Prashant PandeyVimarsh Raina
Jun 19, 2010·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Ciğdem Akalin AkkökØystein Bruserud
Feb 25, 2009·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Rajendra ChaudharySunil Verma
Nov 14, 2013·Journal of Clinical Apheresis·William J WoodallMinh-Ha Tran
Oct 19, 2016·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Muzaffer KeklikErtugrul Keklik
Mar 12, 2020·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Gayathiri K ChellaiyaSangeetha K Nayanar
Oct 31, 2017·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Muzaffer KeklikMurat Sarikoc
Mar 13, 2021·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Sudipta Sekhar DasRathindra Nath Biswas
May 10, 2021·Transfusion clinique et biologique : journal de la Société française de transfusion sanguine·Kanika GargSeema Gupta
Jul 24, 2021·Hematology, Transfusion and Cell Therapy·Sapna ChopraGagandeep Kaur

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