Effect of Electroacupuncture on Natural-Killer Cells and Tumor Size in Patients with Cervical Squamous-Cell Carcinoma: A Randomized Controlled Trial

Medical Acupuncture
Wita SaraswatiThomas Cahyono Sutrisno

Abstract

Background: A natural-killer (NK) cell is a cytotoxic lymphocyte that responds to tumor formation. Electroacupuncture (EA) in patients with cancer, who had chemotherapy, enabled them to maintain their T-cell counts (CD3+, CD4+, and CD8+) and NK-cell activity. Objective: To evaluate NK-cell levels and tumor sizes in patients with cervical squamous-cell carcinoma (SCC) after EA on ST 36 (Zusanli). Design: This study was a randomized, experimental clinical study with a pre-post-test, control group design. Setting The study was performed in the obstetrics and gynecology department, Gynecology Oncology Division of the Rumah Sakit Dokter Soetomo General Hospital, in Surabaya, Jawa Timur, Indonesia, conducted from February 2016 until May 2016. Subjects: Patients with cervical SCC, stages IIb-IIIb (locally advanced)-determined clinically and histopathologically-all of whom had 50 mg/m2/week of cisplatin chemotherapy. The patients were divided, consecutively, into 2 groups by simple random sampling. Intervention: The controls received only received the chemotherapy, while treatment-group patients also had EA 1 day on bilateral ST 36 after each chemotherapy cycle. Outcome Measures: Primary outcomes were percent of NK cells and tumor size...Continue Reading

References

Sep 1, 1986·Gynecologic Oncology·G CastelloA Germano
Nov 25, 1998·Archives of Internal Medicine·J A AstinW L Haskell
Mar 22, 2002·Nature Reviews. Immunology·A Cerwenka, L L Lanier
Oct 26, 2002·The American Journal of Clinical Nutrition·G Harvey AndersonThomas M S Wolever
Oct 7, 2004·The Lancet Oncology·Edna Maria Vissoci ReicheHelena Kaminami Morimoto
Dec 15, 2005·The British Journal of Radiology·A JenaK K Pandey
Jan 6, 2006·The International Journal of Neuroscience·Mehmet Tugrul CabýogluUner Tan
Jan 30, 2008·Evidence-based Complementary and Alternative Medicine : ECAM·Nobuo YamaguchiKenji Kawakita
Oct 7, 2008·Oncogene·I Waldhauer, A Steinle
May 28, 2009·Journal of Gynecologic Oncology·M Farid Aziz
Nov 17, 2009·The Open Virology Journal·Angel Cid-Arregui
Jan 8, 2011·Science·Eric VivierSophie Ugolini
Feb 26, 2011·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayDonald Maxwell Parkin
Jun 27, 2013·Current Pain and Headache Reports·Barbara CagnieMira Meeus
Jan 9, 2014·CA: a Cancer Journal for Clinicians·Rebecca SiegelAhmedin Jemal

❮ Previous
Next ❯

Citations

Sep 5, 2020·OncoTargets and Therapy·Luopei Guo, Keqin Hua

❮ Previous
Next ❯

Methods Mentioned

BETA
hysterectomy
flow-cytometry

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Cancer Biology: Molecular Imaging

Molecular imaging enables noninvasive imaging of key molecules that are crucial to tumor biology. Discover the latest research in molecular imaging in cancer biology in this feed.