Effect of embryo culture media on percentage of males at birth

Human Reproduction
Jinliang ZhuJie Qiao

Abstract

Does embryo culture medium influence the percentage of males at birth? The percentage of males delivered after ICSI cycles using G5™ medium was statistically significantly higher than after cycles where Global, G5™ PLUS, and Quinn's Advantage Media were used. Male and female embryos have different physiologies during preimplantation development. Manipulating the energy substrate and adding growth factors have a differential impact on the development of male and female embryos. This was a retrospective analysis of the percentage of males at birth, and included 4411 singletons born from fresh embryo transfer cycles between January 2011 and August 2013 at the Center for Reproductive Medicine of Third Hospital Peking University. Only singleton gestations were included. Participants were excluded if preimplantation genetic diagnosis, donor oocytes and donor sperm were used. The database between January 2011 and August 2013 was searched with unique medical record number, all patients were present in the database with only one cycle. Demographics, cycle characteristics and the percentage of male babies in the four culture media groups were compared with analysis of variance or χ(2) tests. Multivariable logistic regression was done to ...Continue Reading

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Dec 25, 2015·Taiwanese Journal of Obstetrics & Gynecology·Valentina SotiroskaLars Johansson
Jul 16, 2016·Epigenomics·Habib A Shojaei SaadiClaude Robert
Oct 4, 2016·Acta Diabetologica·Apolonia García-PattersonRosa Corcoy

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