Effect of emulsifier type on droplet disruption in repeated shirasu porous glass membrane homogenization

Langmuir : the ACS Journal of Surfaces and Colloids
Goran T VladisavljevićJulian D McClements

Abstract

The influence of various emulsifier types (anionic, nonionic, and zwitterionic) on the mean particle size, transmembrane flux, and membrane fouling in repeated membrane homogenization using a Shirasu porous glass (SPG) membrane has been investigated. Oil-in-water (O/W) emulsions (40 wt % corn oil stabilized by 0.06-2 wt % sodium dodecyl sulfate (SDS) or 0.1-2 wt % Tween 20 at pH 3 or 0.5-2 wt % beta-lactoglobulin (beta-Lg) at pH 7) were prepared by passing coarsely emulsified feed mixtures five times through the membrane with a mean pore size of 8.0 microm under the transmembrane pressure of 100 kPa. The flux increased as the number of passes increased, tending to a maximum limiting value. The maximum flux for the Tween 20-stabilized emulsions (5-47 m3.m(-2).h(-1)) was smaller than that for the SDS-stabilized emulsions (29-60 m3.m(-2).h(-1)) because less energy was needed for the disruption of a SDS-stabilized droplet due to the lower interfacial tension. The mean particle size after five passes was 4.1-6.8 and 6.4-8.7 mum for 0.1-2 wt % SDS and Tween 20, respectively. The flux in the presence of beta-Lg was much smaller than that in the presence of SDS and Tween 20, which was a consequence of more pronounced membrane fouling, ...Continue Reading

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Mar 15, 2005·Advances in Colloid and Interface Science·Goran T Vladisavljević, Richard A Williams

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Citations

Dec 18, 2013·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Sonja Joseph, Heike Bunjes
May 5, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Zahari VinarovAlex Lips
Apr 25, 2012·Journal of Pharmaceutical Sciences·Sonja Joseph, Heike Bunjes
Sep 4, 2015·Advances in Colloid and Interface Science·Goran T Vladisavljević
May 11, 2011·Journal of Colloid and Interface Science·Khalid ZianiJulie M Goddard
Aug 2, 2016·International Journal of Pharmaceutics·Sandra Gehrmann, Heike Bunjes
Mar 27, 2021·Advances in Colloid and Interface Science·Akmal Nazir, Goran T Vladisavljević

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