PMID: 8964761Mar 1, 1996Paper

Effect of endogenous carbohydrate availability on oral medium-chain triglyceride oxidation during prolonged exercise

Journal of Applied Physiology
Asker E JeukendrupA J Wagenmakers

Abstract

The present study examined the medium-chain triglyceride (MCT) oxidation rate of oral carbohydrate (CHO) + MCT supplements after a glycogen-depletion trial [low glycogen (LG)] and in the glycogen-loaded state [normal-to-high glycogen (HG)]. Eight elite athletes cycled four times 90 min at 50% maximal workload (57% maximal O2 uptake). In two trials, they followed a LG protocol to achieve low-glycogen stores in the leg muscles the evening before the experiment, and in two trials they followed a HG protocol. Subjects received a bolus of 4 ml/kg at the start and 2 ml/kg every 20 min during exercise of either a 15% CHO (long-chain glucose polymer) solution or an equicaloric CHO + MCT suspension. Exogenous MCT oxidation was measured by adding a [1,1,1-13C]trioctanoate tracer to the MCT oil and measuring 13CO2 production in the breath. The results show that 85% of MCT ingested was oxidized in LG and 69% in HG during the 60- to 90-min period. There was no statistically significant difference in MCT utilization between LG and HG. Peak oxidation rates were 0.15 and 0.13 g/min, respectively. MCT contributed 7.6% (LG) and 6.5% (HG) to total energy expenditure during the 60- to 90-min period. Total fatty acid oxidation was significantly ele...Continue Reading

Citations

Mar 1, 1997·Journal of Applied Physiology·A E JeukendrupA J Wagenmakers
Apr 16, 1998·The British Journal of Nutrition·F Brouns, G J van der Vusse
Jul 29, 2003·Journal of Applied Physiology·Marlei E WaltonRonald G Haller
Apr 7, 2010·International Journal of Food Sciences and Nutrition·Miriam E Clegg
Nov 1, 1996·Journal of Applied Physiology·A E JeukendrupA J Wagenmakers
Dec 16, 1998·The British Journal of Nutrition·W H SarisM Vogel
Nov 9, 2019·Journal of the International Society of Sports Nutrition·Nicholas B TillerLaurent Bannock
May 4, 2017·Cell Metabolism·Bret H Goodpaster, Lauren M Sparks
Jun 24, 2004·Nutrition·Asker E Jeukendrup, Sarah Aldred
Jul 20, 1999·Clinics in Sports Medicine·L P Turcotte

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