Effect of endplate conditions and bone mineral density on the compressive strength of the graft-endplate interface in anterior cervical spine fusion

Spine
T H LimG B Andersson

Abstract

Destructive compression tests and finite element analyses were conducted to investigate the biomechanical strength at the graft-endplate interface in anterior cervical fusion. To investigate the effect of endplate thickness, endplate holes, and bone mineral density of the vertebral body on the biomechanical strength of the endplate-graft interface in an anterior interbody fusion of the cervical spine. Subsidence of the graft into the vertebral body is a well-known complication in anterior cervical fusion. However, there is no information in the literature regarding the compressive strength of the graft-endplate interface in relation to the endplate thickness, holes in the endplate, and bone mineral density of the vertebral body. Biomechanical destructive compression tests and finite element analyses were performed in this study. Cervical vertebral bodies (C3-C7) isolated from seven cadaveric cervical spines (age at death 69-86 years, mean 79 years) were used for compression tests. Bone mineral density of each vertebral body was measured using a dual energy radiograph absorptiometry unit. Endplate thickness was measured using three coronal computed tomography images of the middle portion of the vertebral body obtained using a co...Continue Reading

References

Aug 1, 1988·Neurosurgery·N YoganandanS J Larson
Jan 1, 1988·Journal of Spinal Disorders·T HanssonR Jonson
Jan 1, 1987·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·T H HanssonD M Spengler
Jun 1, 1997·British Journal of Neurosurgery·N S BrookeR W Gullan

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Citations

Jan 20, 2004·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·T PitzenW Reith
Apr 22, 2005·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·M R Porto FilhoH L A Defino
Jan 16, 2007·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Pavel Barsa, Petr Suchomel
Aug 23, 2007·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Nathaniel R OrdwayAmir H Fayyazi
Jan 15, 2008·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Magdalena Müller-GerblUlrich Linsenmeier
May 29, 2009·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Alexander AbbushiStefan Nikolaus Kroppenstedt
Nov 28, 2012·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Martin ThalerChristian Bach
Sep 4, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Yu FengbinChen Deyu
Sep 18, 2012·Biomechanics and Modeling in Mechanobiology·Nicola KellyJ Patrick McGarry
Nov 1, 2003·The Spine Journal : Official Journal of the North American Spine Society·Michael J BolestaAnn Marie Chrin
Nov 12, 2003·The Spine Journal : Official Journal of the North American Spine Society·Dino SamartzisHoward S An
Oct 2, 2003·Spine·Eeric TruumeesHarry N Herkowitz
Sep 30, 2004·Spine·Conor O'Neill, Marina Kurgansky
Sep 1, 2007·Spine·Chin-Chang ChengAmir H Fayyazi
Oct 7, 2008·Journal of Spinal Disorders & Techniques·Yu ChenWen Yuan
Aug 10, 2011·Journal of Biomechanical Engineering·Nicolas V JaumardBeth A Winkelstein
Jun 7, 2011·Journal of Neurosurgery. Spine·Morio MatsumotoYoshiaki Toyama
Sep 11, 2013·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Manish K Kasliwal, John E O'Toole
Aug 11, 2005·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Christian H FlammeChristof Hurschler
Feb 8, 2016·Clinical Neurology and Neurosurgery·Jigang LouQuan Gong
Dec 10, 2013·The Spine Journal : Official Journal of the North American Spine Society·Juergen GrauvogelJan Kaminsky
Sep 20, 2011·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Jian ZhouYiqun Ma
Dec 1, 2009·The Spine Journal : Official Journal of the North American Spine Society·Hwan T Hee, Vishal Kundnani
Jan 22, 2013·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Ching-Chi Hsu
Oct 18, 2011·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Nathaniel R OrdwayAmir H Fayyazi
Dec 20, 2014·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Christopher BrenkeMartin Barth
Nov 18, 2005·The Spine Journal : Official Journal of the North American Spine Society·Hans-Peter W van JonbergenPaul W Pavlov

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