PMID: 9434692Jan 22, 1998Paper

Effect of esophageal distention on pressure and electromyographic activity of the pharyngoesophageal sphincter, with identification of the esophagopharyngeal reflex

The Journal of Thoracic and Cardiovascular Surgery
Ahmed Shafik

Abstract

My purpose was to study the effect of balloon-produced esophageal distention on the pharyngoesophageal sphincter to shed light on the mechanism by which esophagopharyngeal reflux is prevented. Nine dogs (mean weight 15.7 +/- 4.3 kg) were used for the study. A balloon-tipped catheter was introduced into the esophagus and a manometric catheter into the pharyngoesophageal sphincter. The pressure response of the pharyngoesophageal sphincter to esophageal distention was recorded. The response was also tested while the esophagus and the pharyngoesophageal sphincter were anesthetized, each separately. In six of nine dogs the electromyographic response of the pharyngoesophageal sphincter to esophageal distention was studied before and after the esophagus was anesthetized. Lower and midesophageal distention produced no pressure changes in the pharyngoesophageal sphincter (p = 0.082). Upper esophageal distention effected an elevation in pharyngoesophageal sphincter pressure (p = 0.024), which showed no further rise when the distending volume was increased. The anesthetized pharyngoesophageal sphincter did not respond to esophageal distention. Likewise, the pharyngoesophageal sphincter did not respond to distention of the anesthetized upp...Continue Reading

References

May 1, 1976·Archives of Internal Medicine·W J Kilman, R K Goyal
Jun 1, 1991·Baillière's Clinical Gastroenterology·I J Cook
Jan 1, 1967·Experimental Neurology·R W DotyA T Storey
Apr 1, 1956·The British Journal of Radiology·G M ARDRAN, F H KEMP
Aug 1, 1952·The British Journal of Radiology·G M ARDRAN, F H KEMP

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Citations

Jun 13, 2006·Current Gastroenterology Reports·Harvey Licht, Robert S Fisher
Oct 1, 2014·The Laryngoscope·Michael DrinnanJanet A Wilson

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