Effect of estimated plasma volume reduction on renal function for acute heart failure differs between patients with preserved and reduced ejection fraction

Circulation. Heart Failure
Makoto TakeiWest Tokyo Heart Failure Registry Investigators

Abstract

The prognostic relevance of plasma volume reduction (PVR) in acute heart failure patients remains unclear because of the confounding hemodynamic effect of left ventricular ejection fraction impairment on kidney function. Subjects enrolled in the West Tokyo Heart Failure Registry were examined. The PV at admission and discharge was estimated from the subjects' body weight and its deviation from the ideal body weight. Patients in the top tertile of estimated PVR were classified as PVR+. Of the 381 patients with acute heart failure, 181 (47.5%) had heart failure with preserved ejection fraction (HFpEF). Estimated PVR was associated with worsening renal function in the HFpEF (odds ratio, 3.28; 95% confidence interval, 1.55-6.96; P=0.002) but not in the heart failure with reduced ejection fraction cohort (odds ratio, 1.22; 95% confidence interval, 0.61-2.42; P=0.57). This association in the HFpEF cohort remained significant after adjusting for a history of hypertension and diabetes mellitus and the estimated glomerular filtration rate (odds ratio, 3.34; 95% confidence interval, 1.52-7.33; P=0.003). The use of intravenous diuretics was a significant predictor of PVR in the HFpEF and heart failure with reduced ejection fraction groups...Continue Reading

References

Dec 23, 1971·The New England Journal of Medicine·P A McKeeW B Kannel
Jan 1, 1996·Nephron·K TabeiY Asano
Jan 23, 2003·Circulation·Ana-Silvia AndroneDonna M Mancini
Jan 13, 2004·Journal of the American College of Cardiology·Daniel E FormanHarlan M Krumholz
Oct 10, 2007·Journal of Cardiac Failure·Kevin DammanHans L Hillege
Mar 29, 2008·Journal of the American College of Cardiology·Anju NohriaJames A Hill
Mar 7, 2009·Current Heart Failure Reports·Travis BenchMathew S Maurer
Apr 3, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Seiichi MatsuoUNKNOWN Collaborators developing the Japanese equation for estimated GFR
Sep 15, 2009·Circulation. Heart Failure·G Michael FelkerUNKNOWN Heart Failure Clinical Research Network Investigators
Dec 9, 2010·European Heart Journal·Barry A Borlaug, Walter J Paulus
Feb 19, 2011·International Journal of Nephrology·Chiara LazzeriGian Franco Gensini
Mar 4, 2011·The New England Journal of Medicine·G Michael FelkerUNKNOWN NHLBI Heart Failure Clinical Research Network
Nov 15, 2011·Current Cardiovascular Risk Reports·Taslima Bhuiyan, Mathew S Maurer
Nov 30, 2011·Journal of Cardiac Failure·Carlos DavilaStuart D Katz
Dec 21, 2012·Kidney International·Joseph F GnanarajJai Radhakrishnan
Mar 12, 2013·European Journal of Heart Failure·Doron AronsonAndrew J Burger
Mar 19, 2013·Journal of the American College of Cardiology·Dirk J van VeldhuisenHans L Hillege
Mar 19, 2013·Circulation Journal : Official Journal of the Japanese Circulation Society·Naoki SatoUNKNOWN TEND Investigators

❮ Previous
Next ❯

Citations

Feb 27, 2016·Journal of Cardiac Failure·Yuya MatsueSteven R Goldsmith
Apr 30, 2016·European Journal of Heart Failure·Toshiyuki NagaiUNKNOWN NaDEF investigators
May 31, 2018·European Journal of Heart Failure·Toshiyuki NagaiJohn G F Cleland
Apr 5, 2019·Circulation Journal : Official Journal of the Japanese Circulation Society·Keitaro AkitaUNKNOWN West Tokyo Heart Failure Registry Investigators
May 28, 2019·Heart and Vessels·Hidenori MoriyamaUNKNOWN West Tokyo Heart Failure Registry Investigators
Sep 20, 2018·Open Heart·Toshiyuki NagaiJohn G F Cleland
Apr 8, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Masatake KobayashiPatrick Rossignol
May 13, 2017·Heart Failure Reviews·Baris AfsarMehmet Kanbay
Nov 7, 2019·Internal and Emergency Medicine·Rajkumar DoshiNageshwara Gullapalli
Apr 20, 2017·Circulation Journal : Official Journal of the Japanese Circulation Society·Shin-Ichi Momomura
Jun 6, 2020·Pharmacology Research & Perspectives·Xiandu LuoYanqing Wu
May 10, 2020·ESC Heart Failure·Hiromi KinIchiro Shiojima
Jan 8, 2021·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Masatake KobayashiPatrick Rossignol

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.